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动脉高血压引起的右心重构:应变评估是否有帮助?

Right heart remodeling induced by arterial hypertension: Could strain assessment be helpful?

机构信息

Department of Internal Medicine and Cardiology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

Clinical Research Unit, Istituto Auxologico Italiano, University of Milan-Bicocca, Meda, Italy.

出版信息

J Clin Hypertens (Greenwich). 2018 Feb;20(2):400-407. doi: 10.1111/jch.13186. Epub 2018 Jan 25.

Abstract

Left ventricular structural and functional changes in patients with arterial hypertension are well established. However, the influence of arterial hypertension on right ventricular (RV) remodeling is still being investigated. The introduction of strain analysis provided an insight into RV function and mechanics. Previous research has demonstrated the predictive value of RV longitudinal strain in patients with various cardiovascular conditions, such as pulmonary hypertension, heart failure, congenital heart diseases, and valvular disease. Nowadays, we are aware of the fact that conventional echocardiographic methods usually do not provide necessary information about RV dysfunction in patients with arterial hypertension, which is why the evaluation of new parameters that could detect RV subtle changes in hypertension is essential. The present review article is an overview of the main principles of RV deformation and a summary of the current knowledge and clinical significance of RV strain in patients with arterial hypertension.

摘要

左心室结构和功能的变化在高血压患者中已经得到了很好的证实。然而,高血压对右心室(RV)重构的影响仍在研究中。应变分析的引入为 RV 功能和力学提供了深入的了解。以前的研究表明,RV 纵向应变在各种心血管疾病患者中具有预测价值,如肺动脉高压、心力衰竭、先天性心脏病和瓣膜病。如今,我们意识到,常规超声心动图方法通常不能提供高血压患者 RV 功能障碍的必要信息,因此评估新的参数来检测高血压中 RV 的细微变化是至关重要的。本文综述了 RV 变形的主要原理,并总结了 RV 应变在高血压患者中的现有知识和临床意义。

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