Anisha Sethi, Sukhjot Kaur, Sunil Gupta Kumar, Sandeep Puri
Department of Skin and S.T.D, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.
Department of Medicine, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.
Int J Trichology. 2016 Jan-Mar;8(1):1-4. doi: 10.4103/0974-7753.179393.
Plica neuropathica also known as "birds nest" is irreversible matting of hair seen in otherwise healthy individuals and is usually associated with use of ionic/herbal soaps, shampoos, parasitic infestations, psychiatric alterations, or neglect. Anagen effluvium is a known side effect of many immunosuppressive drugs. Rarely matting of hair has been reported following azathioprine. We report plica neuropathica in two chronically ill patients on immunosuppressive drugs, that is, azathioprine and methotrexate along with a review of literature of its etiological factors and pathogenesis.
神经性发辫，也称为“鸟巢状发”，是在其他方面健康的个体中出现的不可逆毛发缠结，通常与使用离子/草本肥皂、洗发水、寄生虫感染、精神状态改变或护理不当有关。生长期脱发是许多免疫抑制药物已知的副作用。硫唑嘌呤治疗后很少有毛发缠结的报道。我们报告了两名接受免疫抑制药物（即硫唑嘌呤和甲氨蝶呤）治疗的慢性病患者出现神经性发辫的情况，并对其病因和发病机制的文献进行了综述。
