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特发性炎症性肠病的临床方面:给病理学家的综述

Clinical Aspects of Idiopathic Inflammatory Bowel Disease: A Review for Pathologists.

作者信息

Lee Hwajeong, Westerhoff Maria, Shen Bo, Liu Xiuli

机构信息

From the Department of Pathology and Laboratory Medicine, Albany Medical Center, Albany, New York (Dr Lee); the Department of Anatomic Pathology, University of Washington Medical Center, Seattle (Dr Westerhoff); and the Department of Gastroenterology/Hepatology, Digestive Disease Institute (Dr Shen), and the Department of Pathology, Immunology, and Laboratory Medicine (Dr Liu), University of Florida, Gainesville.

出版信息

Arch Pathol Lab Med. 2016 May;140(5):413-28. doi: 10.5858/arpa.2015-0305-RA.

DOI:10.5858/arpa.2015-0305-RA
PMID:27128299
Abstract

CONTEXT

-Idiopathic inflammatory bowel disease manifests with different clinical phenotypes showing varying behavior and risk for neoplasia. The clinical questions that are posed to pathologists differ depending on phase of the disease and the clinical circumstances. Understanding the clinical aspects of the dynamic disease process will enhance the role of pathology in optimizing the care of patients with inflammatory bowel disease.

OBJECTIVE

-To review clinical and surgical aspects of inflammatory bowel disease that are relevant to practicing pathologists.

DATA SOURCES

-The literature was reviewed.

CONCLUSIONS

-Diagnosis and management of inflammatory bowel disease require an integrated evaluation of clinical, endoscopic, radiologic, and pathologic features. Therefore, close interaction between clinicians and pathologists is crucial. Having this team approach improves understanding of the pertinent clinical and surgical aspects of the disease and assists in the recognition of unusual presentation of variants, as well as mimics of idiopathic inflammatory bowel disease, by pathologists.

摘要

背景

特发性炎症性肠病表现为不同的临床表型,具有不同的行为和肿瘤形成风险。根据疾病阶段和临床情况,向病理学家提出的临床问题也有所不同。了解动态疾病过程的临床方面将增强病理学在优化炎症性肠病患者护理中的作用。

目的

回顾与执业病理学家相关的炎症性肠病的临床和外科方面。

数据来源

对文献进行了综述。

结论

炎症性肠病的诊断和管理需要对临床、内镜、放射学和病理学特征进行综合评估。因此,临床医生和病理学家之间的密切互动至关重要。采用这种团队方法有助于病理学家更好地理解该疾病相关的临床和外科方面,有助于识别变异型的不寻常表现以及特发性炎症性肠病的模仿疾病。

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