Breen Alexander, Breen Alan
Institute for Musculoskeletal Research and Clinical Implementation, Anglo-European College of Chiropractic, 13-15 Parkwood Road, Bournemouth, Dorset BH5 2DF, UK.
School of Design Engineering and Computing, Bournemouth University, Talbot Campus, Poole, Dorset BH12 5BB, UK.
Med Eng Phys. 2016 Jul;38(7):607-614. doi: 10.1016/j.medengphy.2016.03.009. Epub 2016 Apr 26.
Quantitative fluoroscopy (QF) was developed to measure intervertebral mechanics in vivo and has been found to have high repeatability and accuracy for the measurement of intervertebral rotations. However, sagittal plane translation and finite centre of rotation (FCR) are potential measures of stability but have not yet been fully validated for current QF. This study investigated the repeatability and accuracy of QF for measuring these variables. Repeatability was assessed from L2-S1 in 20 human volunteers. Accuracy was investigated using 10 consecutive measurements from each of two pairs of linked and instrumented dry human vertebrae as reference; one which tilted without translation and one which translated without tilt. The results found intra- and inter-observer repeatability for translation to be 1.1mm or less (SEM) with fair to substantial reliability (ICC 0.533-0.998). Intra-observer repeatability of FCR location for inter-vertebral rotations of 5° and above ranged from 1.5mm to 1.8mm (SEM) with moderate to substantial reliability (ICC 0.626-0.988). Inter-observer repeatability for FCR ranged from 1.2mm to 5.7mm, also with moderate to substantial reliability (ICC 0.621-0.878). Reliability was substantial (ICC>0.81) for 10/16 measures for translation and 5/8 for FCR location. Accuracy for translation was 0.1mm (fixed centre) and 2.2mm (moveable centre), with an FCR error of 0.3mm(x) and 0.4mm(y) (fixed centre). This technology was found to have a high level of accuracy and with a few exceptions, moderate to substantial repeatability for the measurement of translation and FCR from fluoroscopic motion sequences.
定量荧光透视法（QF）是为在体内测量椎间力学而开发的，并且已发现其在测量椎间旋转方面具有高重复性和准确性。然而，矢状面平移和有限旋转中心（FCR）是稳定性的潜在测量指标，但目前尚未针对当前的QF进行充分验证。本研究调查了QF测量这些变量的重复性和准确性。在20名人类志愿者中从L2-S1评估了重复性。使用两对相连且装有仪器的干燥人体椎骨中每对的连续10次测量作为参考来研究准确性；一对在无平移的情况下倾斜，另一对在无倾斜的情况下平移。结果发现观察者内和观察者间平移的重复性为1.1毫米或更小（标准误），可靠性为中等至高度可靠（组内相关系数ICC为0.533 - 0.998）。对于5°及以上的椎间旋转，观察者内FCR位置的重复性范围为1.5毫米至1.8毫米（标准误），可靠性为中等至高度可靠（ICC为0.626 - 0.988）。观察者间FCR的重复性范围为1.2毫米至5.7毫米，同样具有中等至高度可靠（ICC为0.621 - 0.878）。对于平移的16项测量中的10项以及FCR位置的8项测量中的五项，可靠性为高度可靠（ICC>0.81）。平移的准确性为0.1毫米（固定中心）和2.2毫米（可移动中心），FCR误差为0.3毫米（x）和0.4毫米（y）（固定中心）。发现该技术具有高度准确性，并且除了少数例外情况，对于从荧光透视运动序列测量平移和FCR具有中等至高度重复性。
