Zhuang Hongjun, Zhu Wenfeng, Yao Zhiyi, Li Min, Zhao Yuliang
CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, PR China.
CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049, PR China.
Talanta. 2016 Jun 1;153:186-90. doi: 10.1016/j.talanta.2016.03.011. Epub 2016 Mar 3.
We present a SERS-based method for the detection of melamine utilizing multi-hydrogen bonding induced charge-transfer (CT) effects. In this system, silver-2-nitro-5-mercaptobenzoic acids (Ag-TNBs) were chosen as the promising probe for melamine sensing. This method relies on the multi-hydrogen-bonding between TNB and melamine which leads to significant Raman frequency shifts in Raman spectra. When being exposure to other potential interfering substances in milk, this system exhibits high selectivity towards melamine. The limit of detection (LOD) of this method is as low as 10(-12)M, which is far below the safety of FDA and USA. The proposed method can be further applied to monitoring the amount of melamine in both caw milk and milk powder.
我们提出了一种基于表面增强拉曼光谱（SERS）的方法，利用多氢键诱导电荷转移（CT）效应来检测三聚氰胺。在该系统中，选择2-硝基-5-巯基苯甲酸银（Ag-TNBs）作为三聚氰胺传感的有前景的探针。该方法依赖于TNB与三聚氰胺之间的多氢键作用，这会导致拉曼光谱中拉曼频率发生显著偏移。当暴露于牛奶中的其他潜在干扰物质时，该系统对三聚氰胺表现出高选择性。该方法的检测限低至10（-12）M，远低于美国食品药品监督管理局（FDA）规定的安全标准。所提出的方法可进一步应用于监测牛奶和奶粉中三聚氰胺的含量。
