Ciardi J E, Rölla G, Bowen W H, Reilly J A
Scand J Dent Res. 1977 Sep;85(6):387-91. doi: 10.1111/j.1600-0722.1977.tb00570.x.
Lipoteichoic acid extracted from cells of S. mutans strain BHT exhibited a high affinity for hydroxyapatite. Phosphate ions, fluoride ions and to a lesser extent human saliva inhibited or reversed this adsorption. Extracellular lipoteichoic acid preparations obtained from the supernatant of cultures of the same bacteria exhibited similar properties. It is suggested that lipoteichoic acids could play a significant role in the colonization of teeth by Gram-positive bacteria and thereby contribute to the formation and pathogenicity of dental plaque.
从变形链球菌BHT菌株细胞中提取的脂磷壁酸对羟基磷灰石具有高亲和力。磷酸根离子、氟离子以及程度稍轻的人类唾液会抑制或逆转这种吸附作用。从相同细菌培养物的上清液中获得的细胞外脂磷壁酸制剂表现出类似的特性。有人提出，脂磷壁酸可能在革兰氏阳性菌在牙齿上的定植过程中发挥重要作用，从而有助于牙菌斑的形成和致病性。
