Knox K W, Markham J L, Wicken A J
Infect Immun. 1976 Mar;13(3):647-52. doi: 10.1128/iai.13.3.647-652.1976.
Antisera prepared against strains of Streptococcus mutans, particularly strain BHT, contain antibodies to the membrane lipoteichoic acid component that will cross-react with lipoteichoic acids from three species of lactobacilli. A more detailed study of the antibodies to strain BHT confirmed that the antibodies are specific for the polyglycerol phosphate component common to the lipoteichoic acids. Sera with a higher hemagglutinating titer could be obtained by injecting disrupted organisms. The partially purified lipoteichoic acid isolated from the culture fluid of S. mutans BHT was also immunogenic antibodies; antibodies were also formed against another unidentified component in this extracellular fraction.
针对变形链球菌菌株,特别是BHT菌株制备的抗血清,含有针对膜脂磷壁酸成分的抗体,这些抗体将与三种乳酸杆菌的脂磷壁酸发生交叉反应。对BHT菌株抗体的更详细研究证实,这些抗体对脂磷壁酸共有的聚甘油磷酸成分具有特异性。通过注射破碎的生物体可以获得血凝滴度更高的血清。从变形链球菌BHT培养液中分离出的部分纯化脂磷壁酸也是免疫原性抗体;还形成了针对该细胞外部分中另一种未鉴定成分的抗体。