Purcell Richard L, Parks Nancy L, Gargiulo Jeanine M, Hamilton William G
Department of Orthopaedics, Walter Reed National Military Medical Center, Bethesda, Maryland; Anderson Orthopaedic Research Institute Alexandria, Virginia.
Anderson Orthopaedic Research Institute Alexandria, Virginia.
J Arthroplasty. 2016 Sep;31(9 Suppl):162-5. doi: 10.1016/j.arth.2016.03.037. Epub 2016 Mar 26.
The orthopedic literature documents that obesity can place patients at increased risk for complications. This is the first study to document the increased risk of infection in obese patients after direct anterior approach (DAA) primary total hip arthroplasty (THA).
We retrospectively evaluated 1621 consecutive primary THAs performed with a DAA. Patients were stratified by body mass index <35 kg/m(2) (group 1) or ≥35 kg/m(2) (group 2). Rates of postoperative infection requiring revision, superficial wound dehiscence, return to the operating room, and total wound complications were compared. There were 1417 cases in group 1 and 204 in group 2.
Five cases in each group had a deep infection, resulting in a significantly higher rate in group 2 (0.35% vs 2.5%, P = .0044, relative risk = 7.1). Superficial wound dehiscence was diagnosed in 13 (0.92%) THA in group 1 and 4 (1.96%) in group 2 (P = .256). The all-cause reoperation rate was 0.92% and 3.43% in each group, respectively (P = .008). The total rate of all studied complications was 1.27% compared to 4.41% (P = .0040, relative risk = 3.5).
This is the first study to report on significantly increased rates of postoperative infection requiring revision in patients with body mass index ≥35 kg/m(2) after anterior approach hip arthroplasty. We believe it is the combination of immune dysfunction and proximity of the anterior incision to the inguinal crease and genitalia with overlying abdominal pannus that contributes to this risk. Further studies comparing other surgical approaches in obese patients are needed to determine if this complication is truly attributable to the DAA alone.
骨科文献记载,肥胖会使患者出现并发症的风险增加。这是第一项记录肥胖患者在直接前路(DAA)初次全髋关节置换术(THA)后感染风险增加的研究。
我们回顾性评估了连续1621例采用DAA进行的初次THA。患者根据体重指数分为<35 kg/m²(第1组)或≥35 kg/m²(第2组)。比较了需要翻修的术后感染率、浅表伤口裂开率、返回手术室率和总伤口并发症率。第1组有1417例,第2组有204例。
每组各有5例深部感染,导致第2组的感染率显著更高(0.35%对2.5%,P = 0.0044,相对风险 = 7.1)。第1组有13例(0.92%)THA被诊断为浅表伤口裂开,第2组有4例(1.96%)(P = 0.256)。每组的全因再次手术率分别为0.92%和3.43%(P = 0.008)。所有研究并发症的总发生率为1.27%,而另一组为4.41%(P = 0.0040,相对风险 = 3.5)。
这是第一项报告体重指数≥35 kg/m²的患者在前路髋关节置换术后需要翻修的术后感染率显著增加的研究。我们认为,免疫功能障碍、前切口靠近腹股沟皱襞和生殖器以及上方的腹部赘肉共同导致了这种风险。需要进一步比较肥胖患者其他手术方式的研究,以确定这种并发症是否真的仅归因于DAA。