Goyal Prashant, Sehgal Shelly, Ghosh Soumyesh, Agrawal Dipti, Singh Sompal
Department of Pathology, Swami Dayanand Hospital , Delhi, India.
Department of Gynecology, Swami Dayanand Hospital , Delhi, India.
Rare Tumors. 2016 Mar 21;8(1):6138. doi: 10.4081/rt.2016.6138.
Carcinoma ex pleomorphic adenoma (CXPA) is exceedingly rare in minor salivary glands of oral cavity. We present a case of CXPA arising from buccal mucosa in a 44-year-old male patient. The man presented to surgery outpatient department with right buccal mucosa swelling. Clinical impression suggests a neoplasm of buccal mucosa and the patient was sent for fine needle aspiration cytology. By examining the cytological smears, possibility of carcinoma was revealed. The mass was dissected and excised with safety margins. Examining Hematoxylin and Eosin slides, final diagnosis of CXPA was given. Patient did not turn for regular follow-ups and presented 1 year after surgery with recurrence at the same site. CXPA is an uncommon malignant tumor with highly aggressive biological behavior. Its occurrence in sites like buccal mucosa is rare. Hence, quite a diagnostic challenge at such sites cause diagnostic difficulties.
多形性腺瘤恶变(CXPA)在口腔小涎腺中极为罕见。我们报告一例发生于一名44岁男性患者颊黏膜的CXPA病例。该男子因右侧颊黏膜肿胀就诊于外科门诊。临床诊断提示为颊黏膜肿瘤,患者被送去做细针穿刺细胞学检查。通过检查细胞学涂片,发现了癌变的可能性。肿物被切除,并确保切缘安全。经苏木精-伊红染色切片检查,最终诊断为CXPA。患者未定期复诊,术后1年在同一部位复发。CXPA是一种罕见的具有高度侵袭性生物学行为的恶性肿瘤。其发生于颊黏膜等部位较为罕见。因此,在此类部位颇具诊断挑战性,会导致诊断困难。