伴有局灶性神经内分泌分化的乙状结肠癌合并溃疡性结肠炎：一例报告
Sigmoid colon carcinoma with focal neuroendocrine differentiation associated with ulcerative colitis: A case report.
作者信息
Rifu Kazuma, Koinuma Koji, Horie Hisanaga, Morimoto Mitsuaki, Kono Yoshihiko, Tahara Makiko, Sakuma Yasunaru, Hosoya Yoshinori, Kitayama Joji, Lefor Alan Kawarai, Sata Naohiro, Suzuki Tsukasa, Fukushima Noriyoshi
机构信息
Department of Surgery, Jichi Medical University, Japan.
Department of Pathology, Jichi Medical University, Japan.
出版信息
Int J Surg Case Rep. 2016;23:151-6. doi: 10.1016/j.ijscr.2016.04.035. Epub 2016 Apr 23.
INTRODUCTION
Neuroendocrine tumors of the colon and rectum are relatively rare compared to sporadic colorectal carcinoma. There are few reports of neuroendocrine tumors of the colon and rectum in patients with ulcerative colitis.
PRESENTATION OF CASE
A patient with sigmoid colon carcinoma with focal neuroendocrine features is presented. A 32-year-old man, who had been followed for ulcerative colitis for 14 years, was found to have carcinoma of the sigmoid colon on routine annual colonoscopy, and he underwent laparoscopic total colectomy. Pathologic examination showed sigmoid colon adenocarcinoma with focal neuroendocrine features.
DISCUSSION
Most colorectal carcinomas associated with inflammatory bowel disease are histologically similar to the sporadic type, and tumors with neuroendocrine features are very unusual.
CONCLUSION
Very rare case of sigmoid colon carcinoma with neuroendocrine features arising in a patient with UC was described.
引言
与散发性结直肠癌相比，结肠和直肠的神经内分泌肿瘤相对少见。关于溃疡性结肠炎患者发生结肠和直肠神经内分泌肿瘤的报道很少。
病例介绍
报告一例具有局灶性神经内分泌特征的乙状结肠癌患者。一名32岁男性，因溃疡性结肠炎已接受随访14年，在常规年度结肠镜检查中发现乙状结肠癌，随后接受了腹腔镜全结肠切除术。病理检查显示为具有局灶性神经内分泌特征的乙状结肠腺癌。
讨论
大多数与炎症性肠病相关的结直肠癌在组织学上与散发性类型相似，具有神经内分泌特征的肿瘤非常罕见。
结论
描述了1例非常罕见的溃疡性结肠炎患者发生的具有神经内分泌特征的乙状结肠癌病例。
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