Miyazaki Hazuki, Mizushima Tsunekazu, Miyoshi Norikatsu, Takahashi Hidekazu, Haraguchi Naotsugu, Hata Taishi, Matsuda Chu, Yamamoto Hirofumi, Mori Masaki, Doki Yuichiro
Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University.
Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University.
Nihon Shokakibyo Gakkai Zasshi. 2020;117(6):521-531. doi: 10.11405/nisshoshi.117.521.
Two cases of neuroendocrine carcinoma, complicated with ulcerative colitis, were examined. Case 1:The patient developed ulcerative colitis at the age of 38, surgery was performed after a diagnosis of rectal cancer at the age of 53, and the patient was diagnosed with neuroendocrine carcinoma by pathological examination after resection. Post-surgery, metastatic nodules were detected in the liver and lungs. The patient is undergoing chemotherapy at this time. Case 2:The patient developed ulcerative colitis at the age of 59;at 72, a sigmoid colon tumor, in addition to multiple liver tumors, was detected. The patient was diagnosed with neuroendocrine carcinoma following biopsy. Chemotherapy was initiated;however, the patient died of cancer 12 months later.
对两例合并溃疡性结肠炎的神经内分泌癌病例进行了检查。病例1：患者38岁时患溃疡性结肠炎，53岁诊断为直肠癌后接受手术，切除术后经病理检查诊断为神经内分泌癌。术后，在肝脏和肺部检测到转移结节。该患者目前正在接受化疗。病例2：患者59岁时患溃疡性结肠炎；72岁时，除多发肝肿瘤外，还检测到乙状结肠肿瘤。活检后该患者被诊断为神经内分泌癌。开始化疗；然而，患者在12个月后死于癌症。
