Saso Srdjan, Clarke Alex, Bracewell-Milnes Timothy, Saso Anja, Al-Memar Maya, Thum Meen-Yau, Yazbek Joseph, Del Priore Giuseppe, Hardiman Paul, Ghaem-Maghami Sadaf, Smith J Richard
Division of Surgery and Cancer, Institute of Reproductive & Developmental Biology, Imperial College London, London, United Kingdom
Department of Plastic and Reconstructive Surgery, Royal Free London, NHS Foundation Trust, London, United Kingdom.
Prog Transplant. 2016 Mar;26(1):28-39. doi: 10.1177/1526924816634840.
Uterine transplantation (UTx).
To explore patients' knowledge of and attitudes toward UTx before and after a short educational intervention via a video and question and answer (Q&A) session.
Large, in-depth survey investigating patients' motivations, aims, and beliefs on UTx.
Imperial College London.
Women diagnosed with absolute uterine factor infertility (AUFI) who were seeking information on UTx and had already volunteered to participate in the study.
A semistructured interview involving a brief baseline questionnaire before a Q&A session and a 20-minute video exploring the main risks and benefits for UTx.
Attitudes of self-referred patients with AUFI toward UTx before and after education focusing on UTx. Rank order of importance of key UTx-related issues.
Forty women were interviewed. Following the video presentation and Q&A session, 97.5% (n = 39) would undergo UTx ahead of surrogacy and adoption in full knowledge that the latter 2 options would be ultimately safer for their own well-being and the fact that the graft could fail even prior to conception. All felt that UTx should take place, and 92.5% saw UTx as achievable.
The study demonstrates a keen interest in UTx, partly because other options seem difficult to access. It is worth noting that people appear to be distancing themselves from the risk. This requires careful assessment in any clinical program. This study is the first to demonstrate a qualitative relationship between patients with AUFI and their curiosity and desire for UTx. It paves the way for forming the introduction into the psychological assessment of a potential patient.
子宫移植（UTx）。
通过视频和问答环节进行短期教育干预，探讨患者在干预前后对子宫移植的了解和态度。
大型深入调查，研究患者对子宫移植的动机、目的和信念。
伦敦帝国理工学院。
被诊断为绝对子宫因素不孕症（AUFI）且正在寻求子宫移植信息并已自愿参与该研究的女性。
在问答环节前进行半结构化访谈，包括一份简短的基线问卷，并播放一段20分钟的视频，探讨子宫移植的主要风险和益处。
以子宫移植为重点的教育前后，自我推荐的AUFI患者对子宫移植的态度。子宫移植相关关键问题的重要性排序。
对40名女性进行了访谈。在视频展示和问答环节之后，97.5%（n = 39）的女性在充分了解代孕和领养对自身健康最终更安全以及移植甚至在受孕前可能失败的情况下，仍会选择子宫移植而非代孕和领养。所有人都认为应该进行子宫移植，92.5%的人认为子宫移植是可行的。
该研究表明患者对子宫移植有着浓厚兴趣，部分原因是其他选择似乎难以实现。值得注意的是，人们似乎在远离风险。在任何临床项目中都需要对此进行仔细评估。本研究首次证明了AUFI患者与其对子宫移植的好奇心和渴望之间的定性关系。它为对潜在患者进行心理评估的引入奠定了基础。
