绝对子宫因素不孕症女性子宫移植的动机：文献系统综述
Motivations for uterus transplantation in women with absolute uterine factor infertility: A systematic review of the literature.
作者信息
Leis Luciana, Tustumi Francisco, Soares-Jr José Maria, Baracat Edmund Chada, Carneiro-D'Albuquerque Luiz Augusto, Ejzenberg Dani, Andraus Wellington
机构信息
Department of Gastroenterology, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brazil.
Department of Gastroenterology, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brazil.
出版信息
Clinics (Sao Paulo). 2025 Apr 13;80:100646. doi: 10.1016/j.clinsp.2025.100646. eCollection 2025.
INTRODUCTION
Uterine transplantation is indicated for women with absolute uterine factor infertility, which is usually associated with congenital causes (the most common being Mayer-Rokitansky-Kuster-Hauser syndrome) or acquired via hysterectomy. For these women, uterus transplantation is the only possibility for them to be able to conceive and have a biological child. The aim of this study was to understand the motivations that lead women with absolute uterine factor infertility to wish to undergo a uterus transplant.
METHODS
A systematic literature review was performed in the following databases: Medline (PubMed), Embase, Cochrane (CENTRAL), Scopus, Web of Science, and LILACS.
RESULTS
439 articles were identified, and nine studies were finally selected. Uterine transplantation was the preferred choice over adoption and surrogacy in most studies (ranging from 45 % to 97.5 %). The main motivations for this type of transplant include the desire to conceive a pregnancy, the desire to have a genetic child, the desire to have control over pregnancy, the physiological repair of the body, the restoration of femininity, and the desire to contribute to science.
CONCLUSION
The motivations for uterus transplantation go far beyond the desire to get pregnant and include personal and unique motivations.
引言
子宫移植适用于患有绝对子宫因素不孕症的女性，这种不孕症通常与先天性原因（最常见的是迈耶-罗基坦斯基-库斯特-豪泽综合征）有关，或因子宫切除而获得。对于这些女性来说，子宫移植是她们能够受孕并生育亲生孩子的唯一可能性。本研究的目的是了解导致患有绝对子宫因素不孕症的女性希望接受子宫移植的动机。
方法
在以下数据库中进行了系统的文献综述：医学在线数据库（PubMed）、Embase、考科蓝图书馆（CENTRAL）、Scopus、科学引文索引数据库和拉丁美洲及加勒比卫生科学数据库。
结果
共识别出439篇文章，最终选定了9项研究。在大多数研究中（范围从45%至97.5%），子宫移植比收养和代孕更受青睐。这种移植的主要动机包括怀孕的愿望、生育亲生孩子的愿望、对怀孕过程的掌控欲、身体的生理修复、女性气质的恢复以及为科学做贡献的愿望。
结论
子宫移植的动机远不止于怀孕的愿望，还包括个人的独特动机。
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