Stanfill Ansley, Hathaway Donna, Bloodworth Robin, Cashion Ann
Department of Health Promotion and Development, University of Pittsburgh, Pittsburgh, PA, USA College of Nursing, University of Tennessee Health Science Center, Memphis, TN, USA
College of Nursing, University of Tennessee Health Science Center, Memphis, TN, USA.
Prog Transplant. 2016 Mar;26(1):70-4. doi: 10.1177/1526924816632118.
Kidney transplant recipients have great risk for gaining significant weight (upward of 10 kg) in the first year posttransplant. Clinical depression can occur in response to life situations and is associated with weight gain.
To explore the association between demographic characteristics, weight change, and depression posttransplantation.
Secondary data analysis on longitudinal data collected for a larger observational study. Demographic characteristics, weight, and Center for Epidemiologic Studies Depression Scale (CES-D) data were obtained at baseline (BL) (time of transplantation), 6, and 12 months posttransplant. The CES-D scores were compared among time points using means, standard deviations, correlations, t tests, and chi-square as well as by multiple regression modeling.
Regional transplant center in the mid-south United States.
Forty-seven kidney transplant recipients (55% female, 57% African American, mean age 52.5 years). Weight change ranged from -18.1 to +24.8 kg.
In all, 62% reported baseline CES-D scores indicative of depression, with lower scores indicating less psychological distress at 6 and 12 months (47% and 49%, respectively). We found no significant differences among CES-D scores at any time point. Regression models found age, race, gender, and weight change to be predictive of CES-D scores at 6 months (P = .04, R (2) = .137). Age was the most influential (P = .008), with older individuals more likely to obtain higher CES-D scores. Since the experience of depression is common at transplant and during the first year, it is important that transplant recipients be evaluated for depression early in the recovery period.
肾移植受者在移植后的第一年有显著体重增加（超过10千克）的巨大风险。临床抑郁症可能因生活状况而发生，且与体重增加有关。
探讨人口统计学特征、体重变化与移植后抑郁症之间的关联。
对为一项更大的观察性研究收集的纵向数据进行二次数据分析。在基线（BL）（移植时）、移植后6个月和12个月获取人口统计学特征、体重以及流行病学研究中心抑郁量表（CES-D）数据。使用均值、标准差、相关性、t检验、卡方检验以及多元回归模型在各时间点之间比较CES-D分数。
美国中南部的区域移植中心。
47名肾移植受者（55%为女性，57%为非裔美国人，平均年龄52.5岁）。体重变化范围为-18.1至+24.8千克。
总体而言，62%的人报告基线CES-D分数表明有抑郁症，分数越低表明在6个月和12个月时心理困扰越少（分别为47%和49%）。我们发现在任何时间点的CES-D分数之间没有显著差异。回归模型发现年龄、种族、性别和体重变化可预测6个月时的CES-D分数（P = .04，R² = .137）。年龄影响最大（P = .008），年龄较大的个体更有可能获得较高的CES-D分数。由于抑郁症在移植时和第一年很常见，因此在康复早期对移植受者进行抑郁症评估很重要。
