Dizman Nazlı, Aydın Bahat Kübra, Özkanlı Şeyma, Özkök Abdullah
Department of Internal Medicine and Nephrology, İstanbul Medeniyet University, Göztepe Training and Research Hospital, İstanbul, Turkey.
Department of Pathology, İstanbul Medeniyet University, Göztepe Training and Research Hospital, İstanbul, Turkey.
Turk Kardiyol Dern Ars. 2016 Apr;44(3):251-5. doi: 10.5543/tkda.2015.94587.
Cholesterol embolization syndrome (CES) is a multisystemic disease with immunological features, and a rare but an important cause of acute kidney injury (AKI) following invasive angiography. It frequently occurs in the elderly male population with extensive atherosclerosis. CES should be considered in the differential diagnosis of AKI following angiography, as prognosis and treatment are completely different from contrast-induced nephropathy. Two cases of CES that developed after invasive angiography are described in the present report. In the first case, renal biopsy was performed, and CES was diagnosed by presence of characteristic renal lesions. The second patient had blue toe syndrome and persistent renal dysfunction.
胆固醇栓塞综合征（CES）是一种具有免疫特征的多系统疾病，是侵入性血管造影术后急性肾损伤（AKI）的罕见但重要原因。它常见于患有广泛动脉粥样硬化的老年男性人群。在血管造影术后AKI的鉴别诊断中应考虑CES，因为其预后和治疗与造影剂肾病完全不同。本报告描述了两例侵入性血管造影术后发生的CES病例。第一例进行了肾活检，通过特征性肾损伤的存在诊断为CES。第二例患者有蓝趾综合征和持续性肾功能不全。
