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GENCOV:一个用Fortran编写的程序,用于生成带有协变量的随机删失生存数据。

GENCOV: a Fortran program that generates randomly censored survival data with covariates.

作者信息

Ciampi A, Chapman J A, Hogg S A, Thiffault J

机构信息

Montreal Children's Hospital Research Institute, Quebec, Canada.

出版信息

Comput Methods Programs Biomed. 1989 May;29(1):51-7. doi: 10.1016/0169-2607(89)90090-4.

Abstract

We present a Fortran program for simulating censored survival data with covariates under the assumption of random censoring. The program generates times distributed according to the uniform distribution, the generalized Gamma distribution, the log-normal distribution and Pettitt's generalized logistic distribution with Box-Cox transformation of the time variable. Covariates can be introduced in the definition of the survival time, resulting in the generalized log-gamma, log-normal and Pettitt's regression models. Thereby the program provides the means for generating censored survival data according to parametric versions of three common regression models for censored survival data: the Accelerated Failure Time, the Proportional Hazards and the Proportional Odds models.

摘要

我们提出了一个Fortran程序,用于在随机删失假设下模拟带有协变量的删失生存数据。该程序生成根据均匀分布、广义伽马分布、对数正态分布以及对时间变量进行Box-Cox变换的佩蒂特广义逻辑分布的时间。协变量可以在生存时间的定义中引入,从而得到广义对数伽马、对数正态和佩蒂特回归模型。由此,该程序提供了根据删失生存数据的三种常见回归模型的参数版本生成删失生存数据的方法:加速失效时间模型、比例风险模型和比例优势模型。

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