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阿替卡因和利多卡因用于上颌第一磨牙症状性不可逆性牙髓炎颊侧浸润麻醉的疗效:一项随机双盲临床试验

Efficacy of Articaine and Lidocaine for Buccal Infiltration of First Maxillary Molars with Symptomatic Irreversible Pulpitis: A Randomized Double-blinded Clinical Trial.

作者信息

Hosseini Hamid Reza, Parirokh Masoud, Nakhaee Nouzar, V Abbott Paul, Samani Syamak

机构信息

Endodontic Department, Dental School, Khorasan Shomali University of Medical Sciences, Bojnord, Iran;

Endodontology Research Center, Kerman University of Medical Sciences, Kerman, Iran;

出版信息

Iran Endod J. 2016 Spring;11(2):79-84. doi: 10.7508/iej.2016.02.001. Epub 2016 Mar 20.

Abstract

INTRODUCTION

The aim of the present study was to compare the efficacy of 2% lidocaine to 4% articaine in buccal infiltration of maxillary first molars with irreversible pulpitis. Moreover, the effect of root length on success of anesthesia irrespective of the type of anesthetic agent was assessed.

METHODS AND MATERIALS

Fifty patients suffering from painful maxillary first molars with irreversible pulpitis received an infiltration injection of either 4% articaine with 1:100000 epinephrine or 2% lidocaine with 1:80000 epinephrine. Each patient recorded their pain score in response to a cold test on a Heft-Parker visual analogue scale (VAS) before commencing the treatment, 5 min following injection, during access preparation, after pulp exposure and during root canal instrumentation. No or mild pain at any stage was considered a success. Data were analyzed using the multivariate logistic regression analysis, chi-square and t tests.

RESULTS

Finally, 47 out of 50 patients were eligible to be included in this study. The anesthetic success rates in the lidocaine and articaine groups were 56.52% and 66.67%, respectively and the difference was not significant (P=0.474). Irrespective of the anesthetic agent, the length of the palatal root (Odds Ratio=0.24, P=0.007) had an adverse effect on anesthetic success. There was an association between longer palatal root length and anesthetic failure.

CONCLUSION

No significant difference was found between 2% lidocaine and 4% articaine in terms of anesthetic success in maxillary first molars with irreversible pulpitis. The length of the palatal root had a significant negative influence on anesthetic success.

摘要

引言

本研究的目的是比较2%利多卡因与4%阿替卡因在上颌第一磨牙不可逆性牙髓炎颊侧浸润麻醉中的效果。此外,评估了牙根长度对麻醉成功率的影响,而不考虑麻醉剂的类型。

方法与材料

50例患有上颌第一磨牙不可逆性牙髓炎且疼痛的患者接受了浸润注射,注射药物为含1:100000肾上腺素的4%阿替卡因或含1:80000肾上腺素的2%利多卡因。每位患者在开始治疗前、注射后5分钟、开髓准备期间、牙髓暴露后及根管预备期间,根据冷测试在Heft-Parker视觉模拟量表(VAS)上记录疼痛评分。在任何阶段无疼痛或轻度疼痛被视为成功。使用多因素逻辑回归分析、卡方检验和t检验对数据进行分析。

结果

最后,50例患者中有47例符合纳入本研究的条件。利多卡因组和阿替卡因组的麻醉成功率分别为56.52%和66.67%,差异无统计学意义(P = 0.474)。无论使用何种麻醉剂,腭根长度(比值比=0.24,P = 0.007)对麻醉成功率有不利影响。腭根长度较长与麻醉失败之间存在关联。

结论

在患有不可逆性牙髓炎的上颌第一磨牙的麻醉成功率方面,2%利多卡因和4%阿替卡因之间未发现显著差异。腭根长度对麻醉成功率有显著的负面影响。

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