[矿物药重金属及有害元素的种类与价态研究]

[Study on species and valence state of heavy metals and deleterious elements of mineral medicine].

作者信息

Han Xu, Luo Jiao-yang, Liu Qiu-tao, Li Yan-jun, Xie Yan-jun, Yang Shi-hai, Yang Mei-hua

出版信息

Zhongguo Zhong Yao Za Zhi. 2015 Dec;40(23):4552-9.

Abstract

As an important part of traditional Chinese medicine (TCM), mineral medicine plays an irreplaceable role. However, little has been reported on its species and valence state of heavy metals and deleterious elements, and also the relevance to pharmacological effect and toxicology. The present paper, in a new perspective, summarized the determination of the species and valence state of heavy metals and deleterious elements in recent years, discussed the progress of the pharmacological effect and toxicology, and prospected for future study which might provide reference for mineral medicine.

摘要

矿物药作为中药的重要组成部分，发挥着不可替代的作用。然而，关于其重金属和有害元素的种类、价态以及与药理作用和毒理学的相关性，报道较少。本文从新的视角综述了近年来重金属和有害元素种类及价态的测定方法，探讨了药理作用和毒理学的研究进展，并对未来研究进行了展望，以期为矿物药研究提供参考。