Mozrzymas Anna
Department of Physics and Biophysics, Wroclaw University of Environmental and Life Sciences, Norwida 25, 50-375 Wroclaw, Poland.
Comb Chem High Throughput Screen. 2016;19(6):481-8. doi: 10.2174/1386207319666160504095717.
The important factor which differentiates gemini surfactants from conventional monomeric surfactants is the spacer group. The molecular connectivity method was used to study the effect of the spacer group on critical micelle concentration of cationic gemini surfactants. Two models were derived employing only Kier and Hall molecular connectivity indices. The relationships were developed for a set of 17 gemini surfactants with various spacer groups only. These models can be used to design the structure of the spacer group and in consequence novel cationic gemini surfactants more active in micelle formation.
将 Gemini 表面活性剂与传统单链表面活性剂区分开来的重要因素是间隔基团。采用分子连接性方法研究了间隔基团对阳离子 Gemini 表面活性剂临界胶束浓度的影响。仅使用基尔（Kier）和霍尔（Hall）分子连接性指数推导了两个模型。仅针对一组具有不同间隔基团的 17 种 Gemini 表面活性剂建立了这些关系。这些模型可用于设计间隔基团的结构，从而设计出在胶束形成方面更具活性的新型阳离子 Gemini 表面活性剂。
