Department Biologie I-Botanik, Ludwig-Maximilians-Universität, Großhaderner Straße 2-4, 82152 Planegg-Martinsried, Germany; Munich Center for Integrated Protein Science CiPSM, Ludwig-Maximilians-Universität, Feodor-Lynen-Strasse 25, 81377 Munich, Germany.
Department Biologie I-Botanik, Ludwig-Maximilians-Universität, Großhaderner Straße 2-4, 82152 Planegg-Martinsried, Germany; Munich Center for Integrated Protein Science CiPSM, Ludwig-Maximilians-Universität, Feodor-Lynen-Strasse 25, 81377 Munich, Germany.
Mol Plant. 2016 Jun 6;9(6):798-812. doi: 10.1016/j.molp.2016.04.014. Epub 2016 Apr 30.
Protein import into chloroplasts has been a focus of research for several decades. The first publications dealing with this fascinating topic appeared in the 1970s. From the initial realization that many plastid proteins are being encoded for in the nucleus and require transport into their target organelle to the identification of import components in the cytosol, chloroplast envelopes, and stroma, as well as elucidation of some mechanistic details, more fascinating aspects are still being unraveled. With this overview, we present a survey of the beginnings of chloroplast protein import research, the first steps on this winding road, and end with a glimpse into the future.
几十年来，蛋白质向叶绿体的输入一直是研究的焦点。最早涉及这个迷人主题的出版物出现在 20 世纪 70 年代。从最初认识到许多质体蛋白是由核编码的，需要运输到它们的靶细胞器，到鉴定细胞质、叶绿体被膜和基质中的输入成分，以及阐明一些机制细节，更多迷人的方面仍在被揭示。通过这篇综述，我们展示了叶绿体蛋白输入研究的开端，这条曲折道路上的第一步，并以对未来的展望结束。
