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内镜检查与影像学检查:鼻窦恶性肿瘤监测方法分析

Endoscopy versus imaging: Analysis of surveillance methods in sinonasal malignancy.

作者信息

Khalili Sammy, Worrall Douglas M, Brooks Steve, Morris Shane M, Farquhar Douglas, Newman Jason G, Learned Kim O, Ahn Peter H, Craig John, Kennedy David W, O'Malley Bert W, Palmer James N, Adappa Nithin D

机构信息

Division of Rhinology, Department of Otorhinolaryngology - Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania.

Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.

出版信息

Head Neck. 2016 Aug;38(8):1229-33. doi: 10.1002/hed.24413. Epub 2016 May 3.

Abstract

BACKGROUND

The purpose of this study was to assess the utility of imaging and endoscopy in posttreatment surveillance of sinonasal malignancies.

METHODS

We conducted a retrospective analysis of primary sinonasal malignancies diagnosed between 2000 and 2014. Posttreatment surveillance included nasal endoscopy and imaging (MRI, CT, and positron emission tomography [PET]/CT). Positive predictive value (PPV), negative predictive value (NPV), specificity, and sensitivity were calculated for each modality and compared.

RESULTS

One hundred nine sinonasal malignancies were identified with 30 recurrences. Endoscopy showed a sensitivity and specificity of 24% and 89%, respectively, whereas imaging was 76% and 90%, respectively. Identifying suspicious symptoms significantly improved the PPV of both endoscopy and imaging. MRI demonstrates the highest PPV when compared with other imaging modalities.

CONCLUSION

Both modalities are necessary in posttreatment surveillance. MRI shows the highest PPV, whereas endoscopy trends toward a higher specificity. PET/CT scans have a high false-positive rate and should be reserved for tumors with a high propensity for distant metastases. © 2016 Wiley Periodicals, Inc. Head Neck 38:1229-1233, 2016.

摘要

背景

本研究的目的是评估影像学检查和内镜检查在鼻窦恶性肿瘤治疗后监测中的作用。

方法

我们对2000年至2014年间诊断的原发性鼻窦恶性肿瘤进行了回顾性分析。治疗后监测包括鼻内镜检查和影像学检查(磁共振成像[MRI]、计算机断层扫描[CT]和正电子发射断层扫描[PET]/CT)。计算每种检查方法的阳性预测值(PPV)、阴性预测值(NPV)、特异性和敏感性,并进行比较。

结果

共确定109例鼻窦恶性肿瘤,其中30例复发。内镜检查的敏感性和特异性分别为24%和89%,而影像学检查分别为76%和90%。识别可疑症状可显著提高内镜检查和影像学检查的PPV。与其他影像学检查方法相比,MRI的PPV最高。

结论

两种检查方法在治疗后监测中都是必要的。MRI的PPV最高,而内镜检查的特异性较高。PET/CT扫描的假阳性率较高,应仅用于远处转移倾向较高的肿瘤。©2016威利期刊公司。头颈外科38:1229 - 1233,2016年。

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