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从韩国分离出的多重耐药鲍曼不动杆菌菌株KBN10P02143的全基因组

Complete genome of the multidrug-resistant Acinetobacter baumannii strain KBN10P02143 isolated from Korea.

作者信息

Lee Yong-Woon, Choe Hanna, Lee Sang-Heon, Kim Kyung Mo, Kam Sin, Kim Byung Kwon, Lee Won-Kil

机构信息

Department of Public Health, Kyungpook National University, Daegu, Republic of Korea.

Microbial Resource Center, Korea Research Institute of Bioscience and Biotechnology, Jeongeup, Republic of Korea.

出版信息

Mem Inst Oswaldo Cruz. 2016 May;111(5):355-8. doi: 10.1590/0074-02760160034. Epub 2016 May 3.

Abstract

Acinetobacter baumannii, a strictly aerobic, non-fermentative, Gram-negative coccobacillary rod-shaped bacterium, is an opportunistic pathogen in humans. We recently isolated a multidrug-resistant A. baumannii strain KBN10P02143 from the pus sample drawn from a surgical patient in South Korea. We report the complete genome of this strain, which consists of 4,139,396 bp (G + C content, 39.08%) with 3,868 protein-coding genes, 73 tRNAs and six rRNA operons. Identification of the genes related to multidrug resistance from this genome and the discovery of a novel conjugative plasmid will increase our understanding of the pathogenicity associated with this species.

摘要

鲍曼不动杆菌是一种严格需氧、不发酵、革兰氏阴性球杆菌,是人类的一种机会致病菌。我们最近从一名韩国外科手术患者的脓液样本中分离出一株多重耐药鲍曼不动杆菌菌株KBN10P02143。我们报告了该菌株的完整基因组,其由4,139,396 bp(G + C含量为39.08%)组成,含有3,868个蛋白质编码基因、73个tRNA和6个rRNA操纵子。从该基因组中鉴定与多重耐药相关的基因以及发现一种新型接合质粒将增进我们对该物种致病性的理解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa43/4878306/e556d67b1541/0074-0276-mioc-111-5-0355-gf02.jpg

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