Rit Simon, Clackdoyle Rolf, Keuschnigg Peter, Steininger Philipp
Université de Lyon, CREATIS, CNRS UMR5220, Inserm U1044, INSA-Lyon, Université Lyon 1, Department of Radiation Oncology, Centre Léon Bérard, 28 rue Laennec, Lyon 69008, France.
Laboratoire Hubert Curien, CNRS and Université Jean Monnet (UMR5516), 18 rue du Professeur Benoit Lauras, Saint Etienne F-42000, France.
Med Phys. 2016 May;43(5):2344. doi: 10.1118/1.4945418.
A new cone-beam CT scanner for image-guided radiotherapy (IGRT) can independently rotate the source and the detector along circular trajectories. Existing reconstruction algorithms are not suitable for this scanning geometry. The authors propose and evaluate a three-dimensional (3D) filtered-backprojection reconstruction for this situation.
The source and the detector trajectories are tuned to image a field-of-view (FOV) that is offset with respect to the center-of-rotation. The new reconstruction formula is derived from the Feldkamp algorithm and results in a similar three-step algorithm: projection weighting, ramp filtering, and weighted backprojection. Simulations of a Shepp Logan digital phantom were used to evaluate the new algorithm with a 10 cm-offset FOV. A real cone-beam CT image with an 8.5 cm-offset FOV was also obtained from projections of an anthropomorphic head phantom.
The quality of the cone-beam CT images reconstructed using the new algorithm was similar to those using the Feldkamp algorithm which is used in conventional cone-beam CT. The real image of the head phantom exhibited comparable image quality to that of existing systems.
The authors have proposed a 3D filtered-backprojection reconstruction for scanners with independent source and detector rotations that is practical and effective. This algorithm forms the basis for exploiting the scanner's unique capabilities in IGRT protocols.
一种用于图像引导放射治疗(IGRT)的新型锥形束CT扫描仪能够使源和探测器沿着圆形轨迹独立旋转。现有的重建算法不适用于这种扫描几何结构。作者针对这种情况提出并评估了一种三维(3D)滤波反投影重建方法。
调整源和探测器的轨迹以成像相对于旋转中心偏移的视野(FOV)。新的重建公式源自费尔德坎普算法,结果是一种类似的三步算法:投影加权、斜坡滤波和加权反投影。使用Shepp Logan数字体模的模拟来评估具有10厘米偏移视野的新算法。还通过拟人化头部体模的投影获得了具有8.5厘米偏移视野的真实锥形束CT图像。
使用新算法重建的锥形束CT图像质量与传统锥形束CT中使用的费尔德坎普算法重建的图像质量相似。头部体模的真实图像显示出与现有系统相当的图像质量。
作者提出了一种适用于具有独立源和探测器旋转的扫描仪的3D滤波反投影重建方法,该方法实用且有效。该算法构成了在IGRT协议中利用扫描仪独特功能的基础。