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直线对称几何源和探测器的静止计算机断层扫描:直接滤波反投影重建。

Stationary computed tomography with source and detector in linear symmetric geometry: Direct filtered backprojection reconstruction.

机构信息

Department of Engineering Physics, Tsinghua University, Beijing, 100084, China.

Key Laboratory of Particle & Radiation Imaging (Tsinghua University), Ministry of Education, Beijing, 100084, China.

出版信息

Med Phys. 2020 Jun;47(5):2222-2236. doi: 10.1002/mp.14058. Epub 2020 Apr 3.

Abstract

PURPOSE

Inverse-geometry computed tomography (IGCT) could have great potential in medical applications and security inspections, and has been actively investigated in recent years. In this work, we explore a special architecture of IGCT in a stationary configuration: symmetric-geometry computed tomography (SGCT), where the x-ray source and detector are linearly distributed in a symmetric design. A direct filtered backprojection (FBP)-type algorithm is developed to analytically reconstruct images from the SGCT projections.

METHODS

In our proposed SGCT system, a big number of x-ray source points equally distributed along a straight-line trajectory will sequentially fire in an ultra-fast manner in one side, and an equispaced detector whose total length is comparable to that of the source will continuously collect data in the opposite side, as the object to be scanned moves into the imaging plane. We firstly present the overall design of SGCT. An FBP-type reconstruction algorithm is then derived for this unique imaging configuration. With finite length of x-ray source and detector arrays, projection data from one segment of SGCT scan are insufficient for an exact reconstruction. As a result, in practical applications, dual-SGCT scan whose detector segments are placed perpendicular to each other, is of particular interest and is proposed. Two segments of SGCT together can make sure that the passing rays cover at least 180 degrees for each and every point if carefully designed. In general, however, there exists a data redundancy problem for a dual-SGCT. So a weighting strategy is developed to maximize the use of projection data collected while avoid image artifacts. In addition, we further extend the fan-beam SGCT to cone beam and obtain a Feldkamp-Davis-Kress (FDK)-type reconstruction algorithm. Finally, we conduct a set of experimental studies both in simulation and on a prototype SGCT system and validate our proposed methods.

RESULTS

A simulation study using the Shepp-Logan head phantom confirms that CT images can be exactly reconstructed from dual-SGCT scan and that our proposed weighting strategy is able to handle the data redundancy properly. Compared with the rebinning-to-parallel-beam method using the forward projection of an abdominal CT dataset, our proposed method is seen to be less sensitive to data truncation. Our algorithm can achieve 10.64 lp/cm of spatial resolution at 50% modulation transfer functions point, higher than that of the rebinning method which can only reach at 9.42 lp/cm even with extremely fine interpolation. Real experiments of a cylindrical object on a prototype SGCT further prove the effectiveness and practicability of the direct FBP method proposed, with similar level of noise performance to rebinning algorithm.

CONCLUSIONS

A new concept of SGCT with linearly distributed source and detector is investigated in this work, in which spinning of sources and detectors is no longer needed during data acquisition, simplifying its system design, development, and manufacturing. A direct FBP-type algorithm is developed for analytical reconstruction from SGCT projection data. Numerical and real experiments validate our method and show that exact CT image can be reconstructed from dual-SGCT scan, where data redundancy problem can be solved by our proposed weighting function.

摘要

目的

逆几何计算机断层扫描(IGCT)在医学应用和安全检查方面具有巨大潜力,近年来受到了广泛关注。在这项工作中,我们研究了一种特殊的 IGCT 结构,即对称几何计算机断层扫描(SGCT),其中 X 射线源和探测器以对称的方式线性分布。我们开发了一种直接滤波反投影(FBP)型算法,用于从 SGCT 投影中解析重建图像。

方法

在我们提出的 SGCT 系统中,大量均匀分布在线性轨迹上的 X 射线源点将以极快的方式在一侧顺序发射,而一个等间距探测器的总长度与源的长度相当,将在另一侧连续采集数据,同时被扫描的物体进入成像平面。我们首先介绍了 SGCT 的总体设计。然后为这种独特的成像配置推导了一种 FBP 型重建算法。由于 X 射线源和探测器阵列的有限长度,来自 SGCT 扫描的一段投影数据不足以进行精确重建。因此,在实际应用中,特别感兴趣的是并置双 SGCT 扫描,其探测器段相互垂直放置。两个 SGCT 段可以确保精心设计的情况下,每个点的射线通过至少 180 度。一般来说,双 SGCT 存在数据冗余问题。因此,我们开发了一种加权策略,以最大化利用收集的投影数据,同时避免图像伪影。此外,我们进一步将扇束 SGCT 扩展到锥形束,并获得 Feldkamp-Davis-Kress(FDK)型重建算法。最后,我们在仿真和原型 SGCT 系统上进行了一系列实验研究,验证了我们提出的方法。

结果

使用 Shepp-Logan 头部体模的模拟研究证实,CT 图像可以从双 SGCT 扫描中精确重建,并且我们提出的加权策略能够正确处理数据冗余问题。与使用腹部 CT 数据集的正向投影进行的重排到平行束方法相比,我们的方法对数据截断的敏感性较低。我们的算法在 50%调制传递函数点处可以达到 10.64 lp/cm 的空间分辨率,高于重排方法,即使使用非常精细的插值,重排方法也只能达到 9.42 lp/cm。在原型 SGCT 上对圆柱形物体的实际实验进一步证明了所提出的直接 FBP 方法的有效性和实用性,其噪声性能与重排算法相当。

结论

本工作研究了一种具有线性分布源和探测器的新型 SGCT 概念,在数据采集过程中不再需要源和探测器的旋转,简化了其系统设计、开发和制造。我们开发了一种直接的 FBP 型算法,用于从 SGCT 投影数据中进行解析重建。数值和实际实验验证了我们的方法,并表明可以从双 SGCT 扫描中重建精确的 CT 图像,我们提出的加权函数可以解决数据冗余问题。

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