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年龄和术前膝关节协会评分是亚洲人全膝关节置换术后结果的重要预测因素。

Age and Preoperative Knee Society Score Are Significant Predictors of Outcomes Among Asians Following Total Knee Arthroplasty.

作者信息

Bin Abd Razak Hamid Rahmatullah, Tan Chuen-Seng, Chen Yongqiang Jerry Delphi, Pang Hee-Nee, Tay Keng-Jin Darren, Chin Pak-Lin, Chia Shi-Lu, Lo Ngai-Nung, Yeo Seng-Jin

机构信息

Department of Orthopaedic Surgery, Singapore General Hospital, Singapore

Saw Swee Hock School of Public Health, National University of Singapore, Singapore.

出版信息

J Bone Joint Surg Am. 2016 May 4;98(9):735-41. doi: 10.2106/JBJS.15.00280.

Abstract

BACKGROUND

The ability to predict patients' functional outcomes will add value to preoperative counseling. The purpose of this study was to evaluate predictors of good outcomes following total knee arthroplasty (TKA) among Asian patients.

METHODS

Registry data from 2006 to 2010 were extracted. The Oxford Knee Score (OKS) and the Short Form (SF)-36 physical component summary (PCS) were used to evaluate outcomes. A "good outcome" was defined as an improvement in scores of greater than or equal to the minimal clinically important difference (MCID) in the primary analysis. The MCID for the OKS was 5, and the MCID for the PCS was 10. For the sensitivity analyses, a "good outcome" was defined as an OKS of <30 and a PCS score of >50. Clinical variables were used to develop a multiple logistic regression model for a good outcome following total knee arthroplasty at 5 years.

RESULTS

Follow-up data were available for 3,062 patients who underwent primary TKA (mean age of 66.4 years; 79.5% female). Eighty-five percent had a good outcome on the basis of the OKS and 83%, on the basis of the SF-36 PCS. Age and preoperative Knee Society score (KSS) were found to be significant predictors. When outcomes were assessed by the MCID, lesser age and lower (worse) preoperative KSS predicted a good outcome at 5 years. When outcomes were assessed by absolute criteria (postoperative scores measured against OKS and PCS thresholds), a higher (better) preoperative KSS predicted a good outcome at 5 years. Body mass index, preoperative flexion range, SF-36 mental component summary (MCS) score, mechanical alignment, sex, education level, ethnicity, operative side, number of comorbidities, type of anesthesia, and type of implant were found not to be significant predictors.

CONCLUSIONS

The majority of Asian patients with osteoarthritis had good outcomes according to the MCID criterion and benefitted from primary TKA. On the basis of our findings, we believe that older patients with a lower (worse) preoperative KSS can be informed that they have a high likelihood of improvement but a lower likelihood of achieving as good a functional outcome as those with better scores.

LEVEL OF EVIDENCE

Prognostic Level IV. See Instructions for Authors for a complete description of levels of evidence.

摘要

背景

预测患者功能结局的能力将为术前咨询增添价值。本研究的目的是评估亚洲患者全膝关节置换术(TKA)后良好结局的预测因素。

方法

提取2006年至2010年的登记数据。采用牛津膝关节评分(OKS)和简明健康状况调查(SF)-36身体成分总结(PCS)来评估结局。在初步分析中,“良好结局”定义为评分改善大于或等于最小临床重要差异(MCID)。OKS的MCID为5,PCS的MCID为10。在敏感性分析中,“良好结局”定义为OKS<30且PCS评分>50。使用临床变量建立一个多因素逻辑回归模型,以预测全膝关节置换术后5年的良好结局。

结果

有3062例行初次TKA患者的随访数据(平均年龄66.4岁;79.5%为女性)。基于OKS,85%的患者结局良好;基于SF-36 PCS,83%的患者结局良好。年龄和术前膝关节协会评分(KSS)被发现是显著的预测因素。当根据MCID评估结局时,年龄较小和术前KSS较低(较差)预测5年时有良好结局。当根据绝对标准(根据OKS和PCS阈值测量的术后评分)评估结局时,术前KSS较高(较好)预测5年时有良好结局。体重指数、术前屈曲范围、SF-36精神成分总结(MCS)评分、机械对线、性别、教育水平、种族、手术侧、合并症数量、麻醉类型和植入物类型被发现不是显著的预测因素。

结论

根据MCID标准,大多数亚洲骨关节炎患者结局良好,并从初次TKA中获益。基于我们的研究结果,我们认为可以告知术前KSS较低(较差)的老年患者,他们改善的可能性很高,但获得与评分较好患者一样好的功能结局的可能性较低。

证据水平

预后IV级。有关证据水平的完整描述,请参阅作者指南。

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