[农民肺：针对嗜热放线菌的IgG亚类反应性]
[Farmer's lung: IgG-subclass reactivities against thermophilic actinomycetes].
作者信息
Reese G, Becker W M, Schlaak M
机构信息
Forschungsinstitut Borstel, Medizinische Klinik.
出版信息
Immun Infekt. 1989 Apr;17(2):59-60.
IgG subclass reactivities of patients suffering from farmer's lung, healthy family members and blood donors were tested for specific binding to Micropolyspora faeni extract by means of immunoblot techniques (IEF-Print, Western Blot). In patients' sera IgG1 and IgG2 had shown the strongest reactivities while IgG3- and IgG4-reactivities were not found in all cases. Strong IgG2-reactivities against acidic proteins (pl 3-5) of M. faeni seem to distinguish between patients and exposed or not exposed controls, respectively.
采用免疫印迹技术（IEF-Print、Western Blot）检测了农民肺患者、健康家庭成员和献血者的IgG亚类与嗜热放线菌提取物的特异性结合反应。在患者血清中，IgG1和IgG2表现出最强的反应性，而并非所有病例都能检测到IgG3和IgG4的反应性。针对嗜热放线菌酸性蛋白（等电点3 - 5）的强IgG2反应性似乎分别区分了患者与暴露或未暴露的对照人群。
Zotero 插件