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2型糖尿病口服药物治疗的认知与体验:定性研究的系统评价与元综合分析

Perceptions and experiences of taking oral medications for the treatment of Type 2 diabetes mellitus: a systematic review and meta-synthesis of qualitative studies.

作者信息

McSharry J, McGowan L, Farmer A J, French D P

机构信息

Health Behaviour Change Research Group, School of Psychology, National University of Ireland, Galway, Ireland.

Manchester Centre for Health Psychology, University of Manchester, Manchester, UK.

出版信息

Diabet Med. 2016 Oct;33(10):1330-8. doi: 10.1111/dme.13152. Epub 2016 Jun 9.

Abstract

AIMS

To explore patients' perceptions and experiences of taking oral medications for the pharmacological management of Type 2 diabetes mellitus.

METHODS

Cinahl, EMBASE, Medline and PsycINFO databases were searched in 2014 to identify qualitative studies exploring patients' perceptions or experiences of taking medications for the management of Type 2 diabetes. Key concepts and themes were extracted and synthesized using meta-ethnography.

RESULTS

Eight studies were included. Primary study findings were synthesized to develop three higher-order constructs that moved beyond the results of individual studies. The first construct, Medications for diabetes: a necessary evil, outlines how patients' negative perceptions of medication risks co-exist with a resounding view that medications are beneficial. Passive patients but active experimenters highlights the contrast between patients' passive acceptance of medication prescriptions and the urge to actively experiment and adjust doses to optimize medication use in daily life. Finally, Taking oral medication for Type 2 diabetes: a unique context describes features specific to the Type 2 diabetes medication experience, including lack of symptoms and the perceived relationship between medication and diet, which may influence adherence.

CONCLUSIONS

Medication-taking for Type 2 diabetes is a unique adherence context, which requires the development of condition-specific interventions. The present findings indicate patients understand the need for medications but adjust dosage and timing in their daily lives. This review suggests providers should acknowledge patient preferences in the development of management strategies, and highlights an opportunity to direct the motivation evident in patients' experimentation towards potentially more beneficial medication-taking behaviours.

摘要

目的

探讨患者对服用口服药物进行2型糖尿病药物治疗的认知和体验。

方法

2014年检索了CINAHL、EMBASE、Medline和PsycINFO数据库,以确定探索患者对服用药物治疗2型糖尿病的认知或体验的定性研究。使用元民族志提取并综合关键概念和主题。

结果

纳入八项研究。对主要研究结果进行综合,以形成超越个别研究结果的三个高阶结构。第一个结构“糖尿病药物:一种必要的恶行”概述了患者对药物风险的负面认知如何与药物有益这一普遍观点并存。“被动患者但积极的试验者”突出了患者对药物处方的被动接受与在日常生活中积极试验和调整剂量以优化药物使用的冲动之间的对比。最后,“服用2型糖尿病口服药物:一种独特的情境”描述了2型糖尿病药物治疗体验的特定特征,包括无症状以及药物与饮食之间的感知关系,这可能会影响依从性。

结论

2型糖尿病的服药是一种独特的依从情境,需要制定针对该疾病的干预措施。目前的研究结果表明患者理解服药的必要性,但会在日常生活中调整剂量和时间。本综述表明,医疗服务提供者在制定管理策略时应承认患者的偏好,并突出了一个机会,即引导患者试验中明显的动机朝着可能更有益的服药行为发展。

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