生殖细胞肿瘤中的循环肿瘤细胞：它们是具有真正预后价值的生物标志物吗？综述。
Circulating tumor cells in germ cell tumors: are those biomarkers of real prognostic value? A review.
作者信息
Cebotaru Cristina Ligia, Olteanu Elena Diana, Antone Nicoleta Zenovia, Buiga Rares, Nagy Viorica
机构信息
Ion Chiricuta Institute of Oncology, Cluj Napoca, Romania; Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania.
Ion Chiricuta Institute of Oncology, Cluj Napoca, Romania.
出版信息
Clujul Med. 2016;89(2):203-11. doi: 10.15386/cjmed-570. Epub 2016 Apr 15.
Analysis of circulating tumor cells from patients with different types of cancer is nowadays a fascinating new tool of research and their number is proven to be useful as a prognostic factor in metastatic breast, colon and prostate cancer patients. Studies are going beyond enumeration, exploring the circulating tumor cells to better understand the mechanisms of tumorigenesis, invasion and metastasis and their value for characterization, prognosis and tailoring of treatment. Few studies investigated the prognostic significance of circulating tumor cells in germ cell tumors. In this review, we examine the possible significance of the detection of circulating tumor cells in this setting.
如今，对不同类型癌症患者循环肿瘤细胞的分析是一项引人入胜的新研究工具，其数量已被证明可作为转移性乳腺癌、结肠癌和前列腺癌患者的预后因素。研究正在超越计数，探索循环肿瘤细胞以更好地了解肿瘤发生、侵袭和转移的机制及其在肿瘤特征描述、预后评估和治疗定制方面的价值。很少有研究调查循环肿瘤细胞在生殖细胞肿瘤中的预后意义。在这篇综述中，我们探讨了在这种情况下检测循环肿瘤细胞的可能意义。
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