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胃癌淋巴结清扫术:争议问题

Lymphadenectomy in gastric cancer: Contentious issues.

作者信息

Garg Pankaj Kumar, Jakhetiya Ashish, Sharma Jyoti, Ray Mukur Dipi, Pandey Durgatosh

机构信息

Pankaj Kumar Garg, Ashish Jakhetiya, Jyoti Sharma, Mukur Dipi Ray, Durgatosh Pandey, Department of Surgical Oncology, Dr BRA Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi 110029, India.

出版信息

World J Gastrointest Surg. 2016 Apr 27;8(4):294-300. doi: 10.4240/wjgs.v8.i4.294.

Abstract

The stomach is the sixth most common cause of cancer worldwide. Surgery is an important component of the multi-modality treatment of the gastric cancer. The extent of lymphadenectomy has been a controversial issue in the surgical management of gastric cancer. The East-Asian surgeons believe that quality-controlled extended lymphadenectomy resulting in better loco-regional control leads to survival benefit in the gastric cancer; contrary to that, many western surgeons believe that extended lymphadenectomy adds to only postoperative morbidity and mortality without significantly enhancing the overall survival. We present a comprehensive review of the lymphadenectomy in the gastric cancer based on the previously published randomized controlled trials.

摘要

胃癌是全球第六大常见癌症病因。手术是胃癌多模式治疗的重要组成部分。淋巴结清扫范围一直是胃癌外科治疗中的一个争议性问题。东亚外科医生认为,质量可控的扩大淋巴结清扫术能更好地实现局部区域控制,从而使胃癌患者获得生存获益;与此相反,许多西方外科医生认为,扩大淋巴结清扫术只会增加术后发病率和死亡率,而不会显著提高总体生存率。我们基于此前发表的随机对照试验,对胃癌淋巴结清扫术进行了全面综述。

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