Zedalis D, Dolen W K, Glover G C, Wiener M B, Selner J C, Weber R W
Allergy-Immunology Service, Fitzsimons Army Medical Center, Aurora, Colo. 80045-5001.
J Allergy Clin Immunol. 1989 May;83(5):973-8. doi: 10.1016/0091-6749(89)90114-0.
A novel method of assessing anterior nasal patency by flexible fiberoptic rhinoscopy was evaluated in two centers by comparison with active anterior rhinomanometry. Rhinoscopy and rhinomanometry were performed 20 times on each of 14 subjects during 14 to 26 minutes. The procedure was videotaped, and nasal airway area was measured from a video monitor. The mean coefficients of variation for rhinoscopy and rhinomanometry were 14% and 19%, respectively. Another investigator examined five subjects by rhinoscopy 30 times in 15 minutes; the mean coefficient of variation was 9%. These means were not significantly different. Rhinoscopy and rhinomanometry were performed at 30-minute intervals for a 6-hour period in 13 subjects. Three investigators independently evaluated results for changes in nasal function characteristic of the nasal cycle. Rhinoscopy detected the nasal cycle in an average of 72% of subjects and rhinomanometry in 49%. Both methods detected the response to topically applied oxymetazoline and methacholine. Results indicate that, whereas the two procedures evaluate different aspects of nasal function, their precision is similar. Rhinoscopy additionally permits evaluation of nasal mucosal changes occurring from disease or treatment.
在两个中心，通过与主动前鼻测压法相比较，对一种通过软性纤维鼻咽喉镜评估前鼻通畅性的新方法进行了评估。在14名受试者身上，于14至26分钟内对每位受试者进行了20次鼻咽喉镜检查和鼻测压。该过程被录像，并且从视频监视器上测量鼻气道面积。鼻咽喉镜检查和鼻测压的平均变异系数分别为14%和19%。另一位研究者在15分钟内对5名受试者进行了30次鼻咽喉镜检查；平均变异系数为9%。这些均值无显著差异。在13名受试者中，每隔30分钟进行一次鼻咽喉镜检查和鼻测压，持续6小时。三名研究者独立评估鼻周期特征性鼻功能变化的结果。鼻咽喉镜检查平均在72%的受试者中检测到鼻周期，鼻测压在49%的受试者中检测到鼻周期。两种方法均检测到了局部应用羟甲唑啉和乙酰甲胆碱后的反应。结果表明，虽然这两种方法评估鼻功能的不同方面，但其精确度相似。此外，鼻咽喉镜检查还允许评估疾病或治疗引起的鼻黏膜变化。
