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迷迭香提取物对手机电磁辐射对腮腺有害影响的保护作用的组织学和组织化学研究

Histological and histochemical study of the protective role of rosemary extract against harmful effect of cell phone electromagnetic radiation on the parotid glands.

作者信息

Ghoneim Fatma M, Arafat Eetmad A

机构信息

Department of Histology and Cell Biology, Faculty of Medicine, Mansoura University, Egypt.

Department of Histology and Cell Biology, Faculty of Medicine, Mansoura University, Egypt; Department of Anatomy, Taif University, Saudi Arabia.

出版信息

Acta Histochem. 2016 Jun;118(5):478-85. doi: 10.1016/j.acthis.2016.04.010. Epub 2016 May 4.

Abstract

Electromagnetic fields (EMFs) are a class of non-ionizing radiation (NIR) that is emitted from mobile phone. It may have hazardous effects on parotid glands. So, we aimed to investigate the histological and histochemical changes of the parotid glands of rats exposed to mobile phone and study the possible protective role of rosemary against its harmful effect. Forty adult male albino rats were used in this study. They were classified into 4 equal groups. Group I (control), group II (control receiving rosemary), group III (mobile phone exposed group) and group IV (mobile exposed, rosemary treated group). Parotid glands were dissected out for histological and histochemical study. Moreover, measurement of oxidative stress markers; malondialdehyde (MDA) and total antioxidant capacity (TAC) was done. The results of this study revealed that rosemary has protective effect through improving the histological and histochemical picture of the parotid gland in addition of its antioxidant effect. It could be concluded from the current study, that exposure of parotid gland of rat models to electromagnetic radiation of mobile phone resulted in structural changes at the level of light and electron microscopic examination which could be explained by oxidative stress effect of mobile phone. Rosemary could play a protective role against this harmful effect through its antioxidant activity.

摘要

电磁场(EMFs)是一类从手机发出的非电离辐射(NIR)。它可能对腮腺产生有害影响。因此,我们旨在研究暴露于手机的大鼠腮腺的组织学和组织化学变化,并探讨迷迭香对其有害影响的可能保护作用。本研究使用了40只成年雄性白化大鼠。它们被分为4个相等的组。第一组(对照组),第二组(接受迷迭香的对照组),第三组(手机暴露组)和第四组(手机暴露、迷迭香处理组)。取出腮腺进行组织学和组织化学研究。此外,还进行了氧化应激标志物丙二醛(MDA)和总抗氧化能力(TAC)的测量。本研究结果表明,迷迭香除了具有抗氧化作用外,还通过改善腮腺的组织学和组织化学状况发挥保护作用。从当前研究可以得出结论,大鼠模型的腮腺暴露于手机的电磁辐射会导致光镜和电镜水平的结构变化,这可以用手机的氧化应激效应来解释。迷迭香可以通过其抗氧化活性对这种有害影响起到保护作用。

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