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单胺氧化酶A与同伴影响在预测成人犯罪行为中的相互作用

The Interplay of MAOA and Peer Influences in Predicting Adult Criminal Behavior.

作者信息

Lu Yi-Fen, Menard Scott

机构信息

Department of Criminal Justice and Criminology, Sam Houston State University, P.O. Box 2296, Huntsville, TX, 77341-2296, USA.

出版信息

Psychiatr Q. 2017 Mar;88(1):115-128. doi: 10.1007/s11126-016-9441-3.

Abstract

Evidence concerning the ability of genetic risk factors to moderate the effects of environments has continued to accumulate over the last decade or so. For the behavioral sciences, this means that genetic risk factors might interact with environmental triggers to influence various human outcomes, including antisocial and aggressive behaviors. The current study seeks to further expand this line of inquiry by examining data drawn from the National Youth Survey Family Study. More specifically, we examined whether a polymorphism in the promoter region of the MAOA gene might condition the influence of exposure to deviant peer groups in the prediction of criminogenic behavior. Our findings offer some mixed evidence that genotype might condition the influence of delinquent peer affiliation on antisocial behavior during the course of human development.

摘要

在过去十年左右的时间里,关于遗传风险因素调节环境影响能力的证据一直在不断积累。对于行为科学来说,这意味着遗传风险因素可能与环境触发因素相互作用,从而影响包括反社会和攻击性行为在内的各种人类行为结果。本研究旨在通过检验来自全国青年调查家庭研究的数据,进一步拓展这一研究方向。更具体地说,我们研究了单胺氧化酶A(MAOA)基因启动子区域的多态性是否会在预测犯罪行为时调节接触不良同伴群体的影响。我们的研究结果提供了一些复杂的证据,表明基因型可能在人类发展过程中调节不良同伴关系对反社会行为的影响。

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