Mehren Christoph, Mayer H Michael, Zandanell Christoph, Siepe Christoph J, Korge Andreas
Spine Center, Schön Klinik München Harlaching, Harlachinger Strasse 51, 81547, Munich, Germany.
Academic Teaching Hospital and Spine Research Institute, Paracelsus Private Medical University Salzburg, Salzburg, Austria.
Clin Orthop Relat Res. 2016 Sep;474(9):2020-7. doi: 10.1007/s11999-016-4883-3. Epub 2016 May 9.
During the last 20 years several less-invasive anterior approaches to the lumbar spine have become standard, including the extreme lateral transpsoas approach. Although it is associated with a lower risk of vascular injury compared with anterior midline approaches, neuromonitoring is considered mandatory to avoid neurologic complications. Interestingly, despite neuromonitoring, the reported risk of neurologic deficits with the extreme lateral transpsoas approach is greater than observed with other anterior approaches. An alternative lateral, oblique, psoas-sparing approach, recently named the oblique lumbar interbody fusion, uses the anatomic pathway between the abdominal vessels anteriorly and the lumbar plexus laterally to decrease the risk of neurologic and vascular injury; however, as yet, little on this new approach has been reported.
QUESTIONS/PURPOSES: We asked: what proportion of patients experienced (1) perioperative complications (overall complications), (2) vascular complications, and (3) neurologic complications after less-invasive anterior lumbar interbody fusion through the oblique lumbar interbody approach at one high-volume center?
We performed a chart review of intra- and perioperative complications of all patients who had undergone minimally invasive anterior lumbar interbody fusion through a lateral psoas-sparing approach from L1 to L5 during a 12-year period (1998-2010). During the study period, the oblique, psoas-sparing approach was the preferred approach of the participating surgeons in this study, and it was performed in 812 patients, all of whom are studied here, and all of whom have complete data for assessment of the short-term (inpatient-only) complications that we studied. In general, we performed this approach whenever possible, although it generally was avoided when a patient previously had undergone an open retro- or transperitoneal abdominal procedure, or previous implantation of hernia mesh in the abdomen. During the study period, posterior fusion techniques were used in an additional 573 patients instead of the oblique lumbar interbody fusion when we needed to decompress the spinal canal beyond what is possible through the anterior approach. In case of spinal stenosis calling for fusion in combination with a high disc space, severe endplate irregularity, or severe biomechanical instability, we combined posterior decompression with oblique lumbar interbody fusion in 367 patients. Complications were evaluated by an independent observer who was not involved in the decision-making process, the operative procedure, nor the postoperative care by reviewing the inpatient records and operative notes.
A total of 3.7% (30/812) of patients who underwent the oblique lumbar interbody fusion experienced a complication intraoperatively or during the hospital stay. During the early postoperative period there were two superficial (0.24%) and three deep (0.37%) wound infections and five superficial (0.62%) and six deep (0.86%) hematomas. There were no abdominal injuries or urologic injuries. The percentage of vascular complications was 0.37% (n = 3). The percentage of neurologic complications was 0.37% (n = 3).
The risk of vascular complications after oblique lumbar interbody fusion seems to be lower compared with reported risk for anterior midline approaches, and the risk of neurologic complications after oblique lumbar interbody fusion seems to be lower than what has been reported with the extreme lateral transpsoas approach; however, we caution readers that head-to-head studies will need to be performed to confirm our very preliminary comparisons and results with the oblique psoas-sparing approach. Similarly, future studies will need to evaluate this approach in terms of later-presenting complications, such as infection and pseudarthrosis formation, which could not be assessed using this inpatient-only approach. Nevertheless, with the results of this study the oblique psoas-sparing approach can be described as a less-invasive alternative for anterior lumbar fusion surgery from L1 to L5 with a low risk of vascular and neurologic damage and without costly intraoperative neuromonitoring tools.
Level IV, therapeutic study.
在过去20年中,几种侵入性较小的腰椎前路手术已成为标准术式,包括极外侧经腰大肌入路。尽管与前路正中入路相比,其血管损伤风险较低,但神经监测仍被认为是避免神经并发症的必要手段。有趣的是,尽管有神经监测,但据报道极外侧经腰大肌入路的神经功能缺损风险高于其他前路手术。一种新的外侧、斜行、保留腰大肌的入路,最近被命名为斜外侧腰椎椎间融合术,利用前方腹部血管和外侧腰丛之间的解剖路径来降低神经和血管损伤的风险;然而,关于这种新入路的报道还很少。
问题/目的:我们想知道:在一个高手术量中心,通过斜外侧腰椎椎间融合术进行微创前路腰椎椎间融合术后,患者出现(1)围手术期并发症(总体并发症)、(2)血管并发症和(3)神经并发症的比例是多少?
我们对1998年至2010年期间12年内所有通过外侧保留腰大肌入路进行微创前路腰椎椎间融合术的患者的术中和围手术期并发症进行了图表回顾。在研究期间,斜行、保留腰大肌入路是本研究中参与手术的外科医生的首选入路,共对812例患者进行了该手术,所有患者均在此进行研究,且所有患者都有完整的数据用于评估我们所研究的短期(仅住院期间)并发症。一般来说,只要有可能我们就采用这种入路,尽管当患者先前接受过开放性腹膜后或经腹手术,或先前在腹部植入过疝修补网时,通常会避免采用这种入路。在研究期间,当需要对椎管进行减压而前路无法完成时,另外573例患者采用了后路融合技术而非斜外侧腰椎椎间融合术。对于需要融合并伴有高椎间盘间隙、严重终板不规则或严重生物力学不稳定的腰椎管狭窄患者,我们在367例患者中将后路减压与斜外侧腰椎椎间融合术相结合。由一名独立观察者通过查阅住院记录和手术记录来评估并发症,该观察者未参与决策过程、手术操作及术后护理。
共有3.7%(30/812)接受斜外侧腰椎椎间融合术的患者在术中或住院期间出现并发症。术后早期有2例表浅(0.24%)和3例深部(0.37%)伤口感染,5例表浅(0.62%)和6例深部(0.86%)血肿。无腹部损伤或泌尿系统损伤。血管并发症的发生率为0.37%(n = 3)。神经并发症的发生率为同样为0.37%(n = 3)。
与报道的前路正中入路风险相比,斜外侧腰椎椎间融合术后血管并发症的风险似乎较低,与极外侧经腰大肌入路相比,斜外侧腰椎椎间融合术后神经并发症的风险似乎也较低;然而,我们提醒读者,需要进行直接对比研究来证实我们对斜行保留腰大肌入路的初步比较和结果。同样,未来的研究需要评估这种入路在后期出现的并发症,如感染和假关节形成方面的情况,而这些并发症无法通过这种仅针对住院患者的研究方法进行评估。尽管如此,根据本研究结果,斜行保留腰大肌入路可被描述为一种从L1至L5的微创前路腰椎融合手术的替代方法,具有较低的血管和神经损伤风险,且无需昂贵的术中神经监测工具。
IV级,治疗性研究。