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L1-L5节段(OLIF25)和L5-S1节段(OLIF51)斜外侧椎间融合术的技术描述及并发症与融合率评估

Technical description of oblique lateral interbody fusion at L1-L5 (OLIF25) and at L5-S1 (OLIF51) and evaluation of complication and fusion rates.

作者信息

Woods Kamal R M, Billys James B, Hynes Richard A

机构信息

Advanced Neurosurgery Associates, 28078 Baxter Rd, Ste. 430, Murrieta, CA 92563, USA.

Florida Orthopaedic Institute, Brandon, FL, USA.

出版信息

Spine J. 2017 Apr;17(4):545-553. doi: 10.1016/j.spinee.2016.10.026. Epub 2016 Nov 21.

Abstract

BACKGROUND CONTEXT

The oblique lateral interbody fusion (OLIF) procedure is aimed at mitigating some of the challenges seen with traditional anterior lumbar interbody fusion (ALIF) and transpsoas lateral lumbar interbody fusion (LLIF), and allows for interbody fusion at L1-S1.

PURPOSE

The study aimed to describe the OLIF technique and assess the complication and fusion rates.

STUDY DESIGN

This is a retrospective cohort study.

PATIENT SAMPLE

The sample is composed of 137 patients who underwent OLIF procedure.

OUTCOME MEASURES

The outcome measures were adverse events within 6 months of surgery: infection, symptomatic pseudarthrosis, hardware failure, vascular injury, perioperative blood transfusion, ureteral injury, bowel injury, renal injury, prolonged postoperative ileus (more than 3 days), incisional hernia, pseudohernia, reoperation, neurologic deficits (weakness, numbness, paresthesia), hip flexion pain, retrograde ejaculation, sympathectomy affecting lower extremities, deep vein thrombosis, pulmonary embolism, myocardial infarction, pneumonia, and cerebrovascular accident. The outcome measures also include fusion and subsidence rates based on computed tomography (CT) done at 6 months postoperatively.

METHODS

Retrospective chart review of 150 consecutive patients was performed to examine the complications associated with OLIF at L1-L5 (OLIF25), OLIF at L5-S1 (OLIF51), and OLIF at L1-L5 combined with OLIF at L5-S1 (OLIF25+OLIF51). Only patients who had at least 6 months of postoperative follow-up, including CT scan at 6 months after surgery, were included. Independent radiology review of CT data was performed to assess fusion and subsidence rates at 6 months.

RESULTS

A total of 137 patients underwent fusion at 340 levels. An overall complication rate of 11.7% was seen. The most common complications were subsidence (4.4%), postoperative ileus (2.9%), and vascular injury (2.9%). Ileus and vascular injuries were only seen in cases including OLIF51. No patient suffered neurologic injury. No cases of ureteral injury, sympathectomy affecting the lower extremities, or visceral injury were seen. Successful fusion was seen at 97.9% of surgical levels.

CONCLUSIONS

Oblique lateral interbody fusion is a safe procedure at L1-L5 as well as L5-S1. The complication profile appears acceptable when compared with LLIF and ALIF. The oblique trajectory mitigates psoas muscle and lumbosacral plexus-related complications seen with the lateral transpsoas approach. Furthermore, there is a high fusion rate based on CT data at 6 months.

摘要

背景

斜外侧椎间融合术(OLIF)旨在缓解传统前路腰椎椎间融合术(ALIF)和经腰大肌外侧腰椎椎间融合术(LLIF)所面临的一些挑战,并可实现L1-S1节段的椎间融合。

目的

本研究旨在描述OLIF技术,并评估其并发症发生率和融合率。

研究设计

这是一项回顾性队列研究。

患者样本

样本由137例行OLIF手术的患者组成。

观察指标

观察指标为术后6个月内的不良事件,包括感染、症状性假关节形成、内固定失败、血管损伤、围手术期输血、输尿管损伤、肠损伤、肾损伤、术后肠梗阻延长(超过3天)、切口疝、假性疝、再次手术、神经功能缺损(无力、麻木、感觉异常)、髋关节屈曲疼痛、逆行射精、影响下肢的交感神经切除术、深静脉血栓形成、肺栓塞、心肌梗死、肺炎和脑血管意外。观察指标还包括术后6个月基于计算机断层扫描(CT)的融合率和沉降率。

方法

对150例连续患者进行回顾性病历审查,以检查L1-L5节段OLIF(OLIF25)、L5-S1节段OLIF(OLIF51)以及L1-L5节段OLIF联合L5-S1节段OLIF(OLIF25+OLIF51)相关的并发症。仅纳入术后至少随访6个月的患者,包括术后6个月的CT扫描。对CT数据进行独立的影像学评估,以评估术后6个月的融合率和沉降率。

结果

共有137例患者在340个节段进行了融合。总体并发症发生率为11.7%。最常见的并发症是沉降(4.4%)、术后肠梗阻(2.9%)和血管损伤(2.9%)。肠梗阻和血管损伤仅见于包含OLIF51的病例。无患者发生神经损伤。未观察到输尿管损伤、影响下肢的交感神经切除术或内脏损伤病例。97.9%的手术节段实现了成功融合。

结论

斜外侧椎间融合术在L1-L5以及L5-S1节段是一种安全的手术。与LLIF和ALIF相比,其并发症情况似乎可以接受。斜向入路减轻了经腰大肌外侧入路所见的腰大肌和腰骶丛相关并发症。此外,基于术后6个月的CT数据,融合率较高。

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