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急性后极部多灶性鳞状色素上皮病变(APMPPE)的光学相干断层扫描血管造影结果

[OCT angiography findings in acute posterior multifocal placoid pigment epitheliopathy (APMPPE)].

作者信息

Maier M, Wehrmann K, Lohmann C P, Feucht N

机构信息

Klinik und Poliklinik für Augenheilkunde, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, 81675, München, Deutschland.

出版信息

Ophthalmologe. 2017 Jan;114(1):60-65. doi: 10.1007/s00347-016-0256-2.

DOI:10.1007/s00347-016-0256-2
PMID:27160929
Abstract

This article reports the case of a 32-year-old female patient who presented with severe spasmodically occurring retrobulbar pain, headaches and light sensitivity. The neurological examination confirmed cephalalgia but no evidence of other neurological symptoms was found. Ophthalmoscopy revealed yellowish patchy lightened spots in the middle periphery. Fluorescein angiography (FLA) and indocyanine green angiography (ICGA) revealed findings typical for acute posterior multifocal placoid pigment epitheliopathy (APMPPE). Hypofluorescent areas visible using ICGA in the early and late phases showed corresponding hypoperfused areas by optical coherence tomography angiography (OCT-A). To the best of our knowledge this is the first description of these findings in OCT-A.

摘要

本文报道了一名32岁女性患者的病例,该患者出现严重的发作性眼球后疼痛、头痛和畏光症状。神经学检查确诊为头痛,但未发现其他神经症状的证据。眼底镜检查发现中周边部有淡黄色斑片状变淡区域。荧光素血管造影(FLA)和吲哚菁绿血管造影(ICGA)显示出急性后极部多灶性扁平色素上皮病变(APMPPE)的典型表现。在ICGA早期和晚期可见的低荧光区域,通过光学相干断层扫描血管造影(OCT-A)显示出相应的低灌注区域。据我们所知,这是OCT-A中对这些发现的首次描述。

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本文引用的文献

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[Clinical applications of OCT angiography].[光学相干断层扫描血管造影术的临床应用]
Ophthalmologe. 2016 Jan;113(1):14-22. doi: 10.1007/s00347-015-0192-6.
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ACUTE POSTERIOR MULTIFOCAL PLACOID PIGMENT EPITHELIOPATHY ON OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY.光学相干断层扫描血管造影术显示的急性后极部多灶性扁平状色素上皮病变
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Vascular rarefaction at the choriocapillaris in acute posterior multifocal placoid pigment epitheliopathy viewed on OCT angiography.在光学相干断层扫描血管造影术中观察到的急性后极部多灶性扁平状色素上皮病变脉络膜毛细血管层的血管稀疏。
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