Alnawaiseh M, Brand C, Lauermann J L, Eter N
Universitäts-Augenklinik Münster, Domagkstr.15, 48149, Münster, Deutschland.
Centrum für Reproduktionsmedizin und Andrologie, Universitätsklinikum Münster, Münster, Deutschland.
Ophthalmologe. 2018 Aug;115(8):659-662. doi: 10.1007/s00347-017-0539-2.
This article presents the normative data for flow density measured using optical coherence tomography (OCT) angiography and the impact of age and gender is evaluated.
In this study 58 eyes from 58 healthy volunteers with no history of any ocular disease or ocular surgery were included. The OCT angiography imaging was performed using the RTVue XR Avanti with the AngioVue (Optovue, Fremont, CA). The macula was imaged using a 3 × 3 mm scan, and the flow density data in the superficial retinal OCT angiogram and deep retinal OCT angiogram were extracted and analyzed. The groups were compared using the Mann-Whitney U‑test and the degree of correlation between two variables was expressed as the Spearman's correlation coefficient (rSp.) RESULTS: The mean subject age was 38.3 ± 14.6 years. The flow density (whole en face) in the deep retinal OCT angiogram was significantly higher compared to the flow density in the superficial retinal OCT angiogram (p < 0.001). There was no significant difference in the mean flow density in superficial and deep OCT angiograms of the macula between males (n = 27) and females (n = 31). There was a significant correlation between the flow density in the deep retinal OCT angiogram and age (rSp. = -0.41, p = 0.001).
Whereas gender has no impact on the flow density measured using OCT angiography, there was a significant correlation between the flow density in the deep retinal OCT angiogram and age.
本文介绍了使用光学相干断层扫描血管造影术（OCTA）测量的血流密度的规范数据，并评估了年龄和性别的影响。
本研究纳入了58名无任何眼部疾病或眼部手术史的健康志愿者的58只眼睛。使用配备AngioVue的RTVue XR Avanti（Optovue，弗里蒙特，加利福尼亚州）进行OCT血管造影成像。使用3×3毫米扫描对黄斑进行成像，并提取和分析视网膜浅层OCT血管造影和视网膜深层OCT血管造影中的血流密度数据。使用Mann-Whitney U检验对各组进行比较，两个变量之间的相关程度用Spearman相关系数（rSp.）表示。结果：受试者的平均年龄为38.3±14.6岁。视网膜深层OCT血管造影中的血流密度（整个表面）明显高于视网膜浅层OCT血管造影中的血流密度（p<0.001）。男性（n = 27）和女性（n = 31）黄斑的浅层和深层OCT血管造影中的平均血流密度没有显著差异。视网膜深层OCT血管造影中的血流密度与年龄之间存在显著相关性（rSp. = -0.41，p = 0.001）。
性别对使用OCT血管造影术测量的血流密度没有影响，而视网膜深层OCT血管造影中的血流密度与年龄之间存在显著相关性。
