Saunders N A, Vandeleur T, Deves J, Salmon A, Gyulay S, Crocker B, Hensley M
University of Newcastle, Royal Newcastle Hospital.
Med J Aust. 1989 Feb 20;150(4):177-82. doi: 10.5694/j.1326-5377.1989.tb136420.x.
Uvulopalatopharyngoplaty was performed in 18 consecutive patients (15 men and three women; mean +/- standard deviation [SD] age, 46.3 +/- 7.5 years) who presented for the treatment of heavy habitual snoring. No attempt was made to select patients who were ideal anatomically for palatal modification. The loudness of snoring was measured during sleep by integrating the output of a calibrated microphone. An assessment before operation showed that nine patients had obstructive sleep apnoea; four patients had an apnoea index of greater than or equal to 25 apnoeas per hour. The patients were overweight and consumed, on average, 38 g of alcohol per day, but these variables did not change after the operation. The postoperative assessment was performed 138 +/- 44 days after uvulopalatopharyngoplasty. Fourteen patients showed a reduction in the loudness of their snoring, although snoring was abolished in one patient only (average snoring loudness in arbitrary units/min of sleep, 2.8 +/- 2.1 before operation compared with 1.4 +/- 1.5 units/min of sleep after the operation; P less than 0.05. The loudest snore in arbitrary units measured 7.1 +/- 3.3 units compared with 4.8 +/- 3.3 units, respectively; P less than 0.05). The percentage of the sleep time that was spent at an arterial oxygen saturation of less than 90% was reduced after uvulopalatopharyngoplasty (28% +/- 32% of total sleep time compared with 17% +/- 24% of total sleep time, respectively; P less than 0.05). There was no change in the apnoea index. The diastolic blood pressure was lower at the postoperative assessment (94 +/- 11 mmHg compared with 87 +/- 8 mmHg; P less than 0.05); six of 10 subjects whose diastolic blood pressures were greater than or equal to 95 mmHg before the operation had a diastolic blood pressure of less than 95 mmHg after uvulopalatopharyngoplasty (P less than 0.02). Computed tomographic scans showed an increase in the upper airway cross-sectional area at 3 cm and 4 cm above the hyoid bone after uvulopalatopharyngoplasty (P less than 0.05). We conclude that uvulopalatopharyngoplasty is an effective treatment for habitual, heavy snoring in many patients, but it is not the treatment of choice for patients with clinically-significant obstructive sleep apnoea.
对18例因重度习惯性打鼾前来治疗的患者(15例男性,3例女性;平均±标准差[SD]年龄,46.3±7.5岁)实施了悬雍垂腭咽成形术。未尝试选择腭部改良解剖结构理想的患者。通过整合校准麦克风的输出在睡眠期间测量打鼾响度。术前评估显示9例患者有阻塞性睡眠呼吸暂停;4例患者的呼吸暂停指数每小时大于或等于25次呼吸暂停。患者超重,平均每天饮酒38克,但这些变量在术后未改变。术后评估在悬雍垂腭咽成形术后138±44天进行。14例患者打鼾响度降低,尽管仅1例患者打鼾消失(术前任意单位/睡眠分钟的平均打鼾响度为2.8±2.1,术后为1.4±1.5单位/睡眠分钟;P<0.05。以任意单位测量的最大打鼾声分别为7.1±3.3单位和4.8±3.3单位;P<0.05)。悬雍垂腭咽成形术后动脉血氧饱和度低于90%的睡眠时间百分比降低(分别占总睡眠时间的28%±32%和17%±24%;P<0.05)。呼吸暂停指数无变化。术后评估时舒张压较低(术前为94±11 mmHg,术后为87±8 mmHg;P<0.05);术前舒张压大于或等于95 mmHg的1十条受试者中有6条在悬雍垂腭咽成形术后舒张压低于95 mmHg(P<0.02)。计算机断层扫描显示悬雍垂腭咽成形术后舌骨上方3 cm和4 cm处上气道横截面积增加(P<0.05)。我们得出结论,悬雍垂腭咽成形术对许多患者的习惯性重度打鼾是一种有效的治疗方法,但对于有临床意义的阻塞性睡眠呼吸暂停患者不是首选治疗方法。