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悬雍垂腭咽成形术后咽部特性的变化。

Changes in pharyngeal properties after uvulopalatopharyngoplasty.

作者信息

Wright S, Haight J, Zamel N, Hoffstein V

机构信息

Dept. of Medicine, St. Michael's Hospital, Toronto, Ontario, Canada.

出版信息

Laryngoscope. 1989 Jan;99(1):62-5. doi: 10.1288/00005537-198901000-00012.

Abstract

Uvulopalatopharyngoplasty is a commonly used modality for surgical treatment of snoring and obstructive sleep apnea. Although this procedure is thought to alter pharyngeal properties, its effect on pharyngeal mechanics has not been studied. The acoustic reflection technique was used to measure pharyngeal area at functional residual capacity and residual volume before and after uvulopalatopharyngoplasty in eight patients referred because of loud snoring. We also calculated the lung volume dependence of pharyngeal area, defined as the percent change in pharyngeal area between functional residual capacity and residual volume, normalized to the area at functional residual capacity. This parameter, which may be related to pharyngeal collapsibility, was obtained before and after uvulopalatopharyngoplasty. Preoperative sleep studies showed that one patient had obstructive sleep apnea (apnea index greater than 10). Uvulopalatopharyngoplasty resulted in a significant increase (p less than 0.01) in pharyngeal area (from 3.14 +/- 0.71 cm2 to 4.25 +/- 1.07 cm2) and residual volume (from 2.49 +/- 0.53 cm2 to 3.91 +/- 0.83 cm2). Following uvulopalatopharyngoplasty, the pharynx became stiffer, as manifested by a reduction in lung volume dependence of pharyngeal area from 19 +/- 12% to 8 +/- 13% (p less than 0.05). Six patients, including the patient with obstructive sleep apnea, reported improvement in snoring. Two patients reported worsening in snoring. One of the two was found to have reduction in pharyngeal area and lung volume dependence of pharyngeal area, and an increase in apnea index from 3 to 33. In selected snorers, uvulopalatopharyngoplasty results in improvement in snoring with a concomitant increase in pharyngeal area and a tendency toward lower pharyngeal collapsibility.

摘要

悬雍垂腭咽成形术是治疗打鼾和阻塞性睡眠呼吸暂停的常用手术方式。尽管该手术被认为会改变咽部特性,但其对咽部力学的影响尚未得到研究。对8例因鼾声过大前来就诊的患者,采用声反射技术测量了悬雍垂腭咽成形术前、后功能残气量和残气量时的咽部面积。我们还计算了咽部面积的肺容积依赖性,即功能残气量与残气量之间咽部面积的变化百分比,以功能残气量时的面积进行标准化。该参数可能与咽部可塌陷性有关,在悬雍垂腭咽成形术前、后均进行了测量。术前睡眠研究显示,1例患者存在阻塞性睡眠呼吸暂停(呼吸暂停指数大于10)。悬雍垂腭咽成形术后,咽部面积显著增加(p<0.01)(从3.14±0.71 cm²增至4.25±1.07 cm²),残气量也显著增加(从2.49±0.53 cm²增至3.91±0.83 cm²)。悬雍垂腭咽成形术后,咽部变得更硬,表现为咽部面积的肺容积依赖性从19±12%降至8±13%(p<0.05)。6例患者,包括患有阻塞性睡眠呼吸暂停的患者,报告打鼾情况有所改善。2例患者报告打鼾情况恶化。其中1例患者咽部面积及咽部面积的肺容积依赖性降低,呼吸暂停指数从3增至33。对于部分打鼾患者,悬雍垂腭咽成形术可改善打鼾情况,同时增加咽部面积,并降低咽部可塌陷性。

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