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天然存在的杂合产物由γ-氨基酸和糖衍生而来，具有潜在的尾对尾醚键。

Naturally occurring hybrids derived from γ-amino acids and sugars with potential tail to tail ether-bonds.

机构信息

State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, P. R. China.

State Key Laboratory Breeding Base of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, 100700, P. R. China.

出版信息

Sci Rep. 2016 May 11;6:25443. doi: 10.1038/srep25443.

DOI:10.1038/srep25443
PMID:27166276
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4863253/
Abstract

The basic substances of life include various amino acids and sugars. To search such molecules is the precondition to understand the essential nature. Here we reported four unprecedented hybrids of γ-amino acids and sugars from the roots of Ranunculus ternatus, which possess potential tail to tail ether-connected (6,6-ether-connected) modes in the sugar moiety. The structures of these hybrids were elucidated by extensive analyses of spectra and calculated electronic circular dichroism (ECD) method.

摘要

生命的基本物质包括各种氨基酸和糖。搜索这些分子是理解本质的前提。在这里，我们从毛茛科植物的根部分离得到了四个前所未有的γ-氨基酸和糖的杂种，它们在糖部分具有潜在的尾对尾醚连接（6,6-醚连接）模式。通过对光谱和计算电子圆二色性（ECD）方法的广泛分析，阐明了这些杂种的结构。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6bb/4863253/3e286c9d4855/srep25443-f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6bb/4863253/231967cf43c2/srep25443-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6bb/4863253/5111fb0f7fe8/srep25443-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6bb/4863253/9deaf0daddf4/srep25443-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6bb/4863253/812ca71368c7/srep25443-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6bb/4863253/a94cdebccb5e/srep25443-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6bb/4863253/3e286c9d4855/srep25443-f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6bb/4863253/231967cf43c2/srep25443-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6bb/4863253/5111fb0f7fe8/srep25443-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6bb/4863253/9deaf0daddf4/srep25443-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6bb/4863253/812ca71368c7/srep25443-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6bb/4863253/a94cdebccb5e/srep25443-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6bb/4863253/3e286c9d4855/srep25443-f6.jpg

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