Lutze M, Weigel K, Brock M
Neurochirurgia (Stuttg). 1989 Mar;32(2):50-1. doi: 10.1055/s-2008-1054001.
The hormone calcitonin has proved itself for some years in the treatment of chronic pain syndromes. In addition to its known influence on calcium exchange it gives vise to an analgesic effect within the central nervous system and this follows systemic administration or after bolus intrathecal injection. Two patients with chronic non malignant pain are presented in whom continuous delivery pumps have been used for intrathecal Lachs-Calcitonin (Karil, Fa. Sandoz).
多年来，降钙素已在慢性疼痛综合征的治疗中得到验证。除了其对钙交换的已知影响外，它还能在中枢神经系统内产生镇痛作用，这种作用在全身给药或鞘内推注后即可出现。本文介绍了两名慢性非恶性疼痛患者，他们使用了持续给药泵进行鞘内注射拉克氏降钙素（卡立，山德士公司）。
