Loew F, Jacot des Combes B, Gauthey L, Herrmann F
Hôpital de Gériatrie, Institutions Universitaires de Gériatrie, Département de Médecine, Genève.
Nephrologie. 1989;10(1):5-10.
In elderly and very old patients, arterial hypertension is a major cardiovascular risk factor. However, its management is still controversial. In this review paper, the effects of old age on cardiovascular homeostasis are discussed. Because of less efficient baroreflexes, increased blood pressure variability, postural hypotension, impaired renal and electrolytes regulation, elderly patients are more prone to side effects of treatment. Special attention should be paid to the blood pressure measurements: in this respect, ambulatory non invasive blood pressure profiles can be particularly helpful for the diagnosis and the control of hypertension. A practical approach acknowledging specific aspects of old age and recent advances in antihypertensive therapy is proposed.
在老年和高龄患者中，动脉高血压是主要的心血管危险因素。然而，其治疗仍存在争议。在这篇综述文章中，讨论了衰老对心血管稳态的影响。由于压力反射效率降低、血压变异性增加、体位性低血压、肾脏及电解质调节受损，老年患者更容易出现治疗副作用。应特别关注血压测量：在这方面，动态无创血压监测对高血压的诊断和控制可能特别有帮助。本文提出了一种考虑到老年患者特殊情况及抗高血压治疗最新进展的实用方法。
