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衰老与高血压。

Aging and hypertension.

作者信息

Fukutomi Motoki, Kario Kazuomi

机构信息

Department of Cardiology, Yamaguchi Grand Medical Center, 77 Osaki, Hofu, Yamaguchi 747-8511, Japan.

出版信息

Expert Rev Cardiovasc Ther. 2010 Nov;8(11):1531-9. doi: 10.1586/erc.10.78.

Abstract

Aging is known to be a dominant risk factor in the progression of hypertension. Thus, accompanied by an increasing mean age of the population in developed countries, prevention and management of hypertension in the elderly is a task of pressing urgency. Age-associated blood pressure elevation is a result of the aging process in organ systems, which play a key role in the regulation of blood pressure. In addition, advanced aging of the cardiovascular system contributes to the presence of a varied phenotype in elderly hypertension, such as nocturnal hypertension and morning hypertension. Therefore, in order to detect and treat age-associated hypertension appropriately, it is important to assess ambulatory blood pressure monitoring throughout the 24-h period.

摘要

众所周知,衰老在高血压进展过程中是一个主要风险因素。因此,随着发达国家人口平均年龄不断增加,老年人高血压的预防和管理成为一项紧迫任务。与年龄相关的血压升高是器官系统衰老过程的结果,而这些器官系统在血压调节中起关键作用。此外,心血管系统的高度老化导致老年高血压存在多种表型,如夜间高血压和清晨高血压。因此,为了适当地检测和治疗与年龄相关的高血压,在24小时内评估动态血压监测很重要。

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