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1型神经纤维瘤病相关的胃肠道炎性息肉

Neurofibromatosis Type 1-Associated Inflammatory Polyp of the Gastrointestinal Tract.

作者信息

Goto Keisuke, Hirosaki Takuya, Masubuchi Mariko

机构信息

1 Kainan Hospital, Yatomi, Aichi, Japan.

出版信息

Int J Surg Pathol. 2017 Feb;25(1):65-68. doi: 10.1177/1066896916648772. Epub 2016 Jul 28.

DOI:10.1177/1066896916648772
PMID:27170677
Abstract

The entity known as "juvenile-like (inflammatory/hyperplastic) mucosal polyps of the gastrointestinal tract in neurofibromatosis type 1 (NF1)" was recently proposed, but is not well known. Here, we describe the characteristics of this entity in a surgically resected case. The hemorrhagic 2 × 1 cm-sized polyp was resected from the ascending colon of a 55-year-old male NF1 patient. The polyp was composed of characteristic multiple mucosal protrusions and submucosal elements that included vasculopathic changes. Histologically, this lesion was similar to an inflammatory fibroid polyp rather than juvenile or hyperplastic polyps. This disease could be a distinct entity, and "inflammatory vasculopathic polyp" would be a suitable name.

摘要

最近提出了一种名为“1型神经纤维瘤病(NF1)患者胃肠道的幼年样(炎症性/增生性)黏膜息肉”的实体,但目前对此了解不多。在此,我们描述了一例手术切除病例中该实体的特征。从一名55岁男性NF1患者的升结肠切除了一个2×1厘米大小的出血性息肉。该息肉由特征性的多个黏膜突起和包含血管病变改变的黏膜下成分组成。组织学上,该病变类似于炎性纤维瘤性息肉,而非幼年性或增生性息肉。这种疾病可能是一种独特的实体,“炎性血管病变性息肉”可能是一个合适的名称。

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引用本文的文献

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A Case for Gastrointestinal Specific Polyps in Neurofibromatosis Type I.1型神经纤维瘤病中胃肠道特异性息肉病例
Gastro Hep Adv. 2025 Apr 21;4(7):100679. doi: 10.1016/j.gastha.2025.100679. eCollection 2025.
2
Inflammatory/juvenile-like polyps in neurofibromatosis type 1 associated with epithelial dysplasia.NF1 相关炎症/幼年样息肉伴上皮异型增生。
Virchows Arch. 2024 May;484(5):865-868. doi: 10.1007/s00428-024-03769-w. Epub 2024 Feb 24.
3
Gastrointestinal juvenile-like (inflammatory/hyperplastic) mucosal polyps in neurofibromatosis type 1 with no concurrent genetic or clinical evidence of other syndromes.
胃肠道幼年型(炎症/增生性)黏膜息肉,伴 1 型神经纤维瘤病,无其他综合征的遗传或临床证据。
Virchows Arch. 2019 Feb;474(2):259-264. doi: 10.1007/s00428-018-2462-6. Epub 2018 Oct 1.
4
Coexistence of Juvenile-Like Polyp with Neurofibroma at the Gastroesophageal Junction in an Adult with Neurofibromatosis Type I.一名患有Ⅰ型神经纤维瘤病的成年患者食管胃交界处存在少年型息肉与神经纤维瘤并存的情况。
Case Rep Pathol. 2017;2017:9836759. doi: 10.1155/2017/9836759. Epub 2017 Jan 12.