Department of Pathology, Saint-Antoine Hospital, AP-HP, Sorbonne Université, Paris, France.
Centre for Digestive Endoscopy, Saint-Antoine Hospital, AP-HP, Sorbonne Université, Paris, France.
Virchows Arch. 2024 May;484(5):865-868. doi: 10.1007/s00428-024-03769-w. Epub 2024 Feb 24.
The term "juvenile-like (inflammatory/hyperplastic) mucosal polyps" (JLIHMP) has been recently introduced to describe a spectrum of polypoid lesions in patients with neurofibromatosis type 1 (NF-1). Due to the scarce number of reported cases and histopathological similarities with entities such as sporadic/syndromic juvenile polyps or inflammatory fibroid polyps, this entity remains a subject of debate. We describe herein a case of multiple JLIHMPs in a patient with NF-1, and we document the presence of low-grade dysplasia within one of these polyps.
最近引入了“幼年样（炎症/增生性）黏膜息肉”（JLIHMP）这一术语来描述 1 型神经纤维瘤病（NF-1）患者的一系列息肉样病变。由于报道的病例数量较少，且与散发性/综合征性幼年息肉或炎症纤维瘤性息肉等实体具有组织病理学相似性，因此该实体仍然存在争议。我们在此描述了一例 NF-1 患者的多个 JLIHMP，并记录了其中一个息肉存在低级别异型增生。
