Kim Hee Joo, Lee Min-Geol
Department of Dermatology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Australas J Dermatol. 2017 Nov;58(4):e193-e198. doi: 10.1111/ajd.12496. Epub 2016 May 13.
Cholinergic urticaria (ChU) is characterized by small wheals induced by an elevated core temperature. Its pathomechanism and various aspects of its clinical manifestations are still poorly understood. This study aimed to evaluate the spectrum of symptoms and signs of ChU in Korean patients.
We retrospectively reviewed the medical records of patients diagnosed with ChU.
Among 203 patients (188 male and 15 female), 29 (14%) complained only of an itching or burning sensation without visible skin eruption. The prevalence of ChU was highest in patients in their twenties (56%), while most patients first developed their symptoms during their teens (65%). Patients with a visible skin eruption showed better responses to antihistamines than those without skin lesions.
Physicians should consider the varying manifestations of ChU, including cholinergic pruritus and erythema as minor variants, to provide better management of ChU.
胆碱能性荨麻疹（ChU）的特征是核心体温升高诱发小风团。其发病机制及临床表现的各个方面仍知之甚少。本研究旨在评估韩国患者中ChU的症状和体征范围。
我们回顾性分析了诊断为ChU的患者的病历。
在203例患者（188例男性和15例女性）中，29例（14%）仅主诉有瘙痒或烧灼感，无可见皮疹。ChU在二十多岁的患者中患病率最高（56%），而大多数患者在十几岁时首次出现症状（65%）。有可见皮疹的患者对抗组胺药的反应比无皮肤损害的患者更好。
医生应考虑ChU的不同表现，包括将胆碱能性瘙痒和红斑视为轻微变异型，以便更好地管理ChU。
