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免疫功能正常的急性巨细胞病毒性结肠炎患者发生肺栓塞。

Pulmonary embolism in an immunocompetent patient with acute cytomegalovirus colitis.

作者信息

Chou Jen-Wei, Cheng Ken-Sheng

机构信息

Division of Gastroenterology and Hepatology, Department of Internal Medicine, China Medical University Hospital, School of Medicine, China Medical University, Taichung, Taiwan, Republic of China.

出版信息

Intest Res. 2016 Apr;14(2):187-90. doi: 10.5217/ir.2016.14.2.187. Epub 2016 Apr 27.

Abstract

Acute cytomegalovirus (CMV) infection occurs commonly in immunocompromised and immunocompetent patients, but is usually asymptomatic in the latter. Vascular events associated with acute CMV infection have been described, but are rare. Hence, such events are rarely reported in the literature. We report a case of pulmonary embolism secondary to acute CMV colitis in an immunocompetent 78-year-old man. The patient presented with fever and diarrhea. Colonic ulcers were diagnosed based on colonoscopy findings, and CMV was the proven etiology on pathological examination. The patient subsequently experienced acute respiratory failure. Pulmonary embolism was diagnosed based on the chest radiography and computed tomography findings. A diagnosis of acute CMV colitis complicated by pulmonary embolism was made. The patient was successfully treated with intravenous administration of unfractionated heparin and intravenous ganciclovir.

摘要

急性巨细胞病毒(CMV)感染常见于免疫功能低下和免疫功能正常的患者,但在后者中通常无症状。与急性CMV感染相关的血管事件已有报道,但很罕见。因此,此类事件在文献中很少被报道。我们报告一例78岁免疫功能正常男性因急性CMV结肠炎继发肺栓塞的病例。该患者出现发热和腹泻。根据结肠镜检查结果诊断为结肠溃疡,病理检查证实病因是CMV。患者随后出现急性呼吸衰竭。根据胸部X线和计算机断层扫描结果诊断为肺栓塞。诊断为急性CMV结肠炎并发肺栓塞。患者通过静脉注射普通肝素和静脉注射更昔洛韦成功治愈。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/161e/4863054/b1f6ee968ab2/ir-14-187-g001.jpg

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