Maxwell Branden M, Brunell Marla K, Olsen Cara H, Bentzel David E
Center for Laboratory Animal Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
J Am Assoc Lab Anim Sci. 2016;55(3):331-5.
Body temperature is a common physiologic parameter measured in both clinical and research settings, with rectal thermometry being implied as the 'gold standard.' However, rectal thermometry usually requires physical or chemical restraint, potentially causing falsely elevated readings due to animal stress. A less stressful method may eliminate this confounding variable. The current study compared 2 types of digital rectal thermometers-a calibrated digital thermometer and a common digital thermometer-with an implantable subcutaneous transponder microchip. Microchips were implanted subcutaneously between the shoulder blades of 16 ferrets (8 male, 8 female), and temperatures were measured twice from the microchip reader and once from each of the rectal thermometers. Results demonstrated the microchip temperature readings had very good to good correlation and agreement to those from both of the rectal thermometers. This study indicates that implantable temperature-sensing microchips are a reliable alternative to rectal thermometry for monitoring body temperature in ferrets.
体温是临床和研究环境中都要测量的常见生理参数,直肠测温法被视为“金标准”。然而,直肠测温通常需要物理或化学约束,这可能会因动物应激导致读数假性升高。一种压力较小的方法可能会消除这个混杂变量。本研究比较了两种类型的数字直肠温度计——一种校准数字温度计和一种普通数字温度计——与一种可植入皮下的应答器微芯片。将微芯片皮下植入16只雪貂(8只雄性,8只雌性)的肩胛骨之间,通过微芯片读取器测量温度两次,并用每种直肠温度计测量一次。结果表明,微芯片温度读数与两种直肠温度计的读数具有非常好到良好的相关性和一致性。这项研究表明,可植入温度感应微芯片是雪貂体温监测中直肠测温法的可靠替代方法。