García-Herrera Claudio M, Bustos Claudio A, Celentano Diego J, Ortega Roberto
a Departamento de Ingeniería Mecánica , Universidad de Santiago de Chile, USACH , Santiago de Chile , Chile .
b Departamento de Ingeniería Mecánica y Metalúrgica, Instituto de Ingeniería Biológica y Médica (IIBM) , Pontificia Universidad Católica de Chile (PUC) , Santiago de Chile , Chile .
Comput Methods Biomech Biomed Engin. 2016 Dec;19(16):1738-1748. doi: 10.1080/10255842.2016.1183125. Epub 2016 May 13.
This work presents experiments, modelling and numerical simulation aimed at describing the mechanical response of human ascending aortas in the ring opening test. The objective is to quantify, from the opening angles measured in the test, the residual stress distribution along the artery wall and, afterwards, how this stress pattern changes when the artery is subjected to standard physiological pressures. The cases studied correspond to four groups including both healthy and pathological arteries. The tissues are characterized via tensile test measurements that enable to derive the material parameters of two constitutive models adopted in the present analysis. Overall, the numerical results obtained for all groups were found to be a useful data that allow to estimate the residual stress and their influence on the vessels under normal and hypertension physiological conditions.
这项工作展示了旨在描述人体升主动脉在开口试验中的力学响应的实验、建模和数值模拟。目的是根据试验中测量的开口角度，量化沿动脉壁的残余应力分布，然后量化当动脉承受标准生理压力时这种应力模式如何变化。所研究的案例对应于包括健康和病变动脉的四组。通过拉伸试验测量对组织进行表征，从而能够推导出本分析中采用的两个本构模型的材料参数。总体而言，所有组获得的数值结果被发现是有用的数据，可用于估计正常和高血压生理条件下的残余应力及其对血管的影响。
