Tan Antoinette R
Levine Cancer Institute, Carolinas HealthCare System, Charlotte, NC.
Semin Oncol. 2016 Jun;43(3):331-4. doi: 10.1053/j.seminoncol.2016.02.030. Epub 2016 Feb 23.
Breast cancer may present with cutaneous symptoms. The skin manifestations of breast cancer are varied. Some of the more common clinical presentations of metastatic cutaneous lesions from breast cancer will be described. Paraneoplastic cutaneous dermatoses have been reported as markers of breast malignancy and include erythema gyratum repens, acquired ichthyosis, dermatomyositis, multicentric reticulohistiocytosis, and hypertrichosis lanuginosa acquisita. Mammary Paget's disease, often associated with an underlying breast cancer, and Cowden syndrome, which has an increased risk of breast malignancy, each have specific dermatologic findings. Recognition of these distinct cutaneous signs is important in the investigation of either newly diagnosed or recurrent breast cancer.
乳腺癌可能会出现皮肤症状。乳腺癌的皮肤表现多种多样。本文将描述一些乳腺癌转移性皮肤病变更常见的临床表现。副肿瘤性皮肤皮肤病已被报道为乳腺恶性肿瘤的标志物,包括回状红斑、获得性鱼鳞病、皮肌炎、多中心网状组织细胞增多症和获得性胎毛增多症。乳腺佩吉特病通常与潜在的乳腺癌相关,而考登综合征患乳腺恶性肿瘤的风险增加,它们都有特定的皮肤学表现。认识这些独特的皮肤体征对于新诊断或复发性乳腺癌的调查很重要。