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有证据表明,在19号染色体上,SE位于LU的远端。

Evidence that SE is distal to LU on chromosome 19q.

作者信息

Zelinski T, Coghlan G, Greenberg C R, McAlpine P J, Lewis M

机构信息

Department of Pediatrics, Faculty of Medicine, University of Manitoba, Winnipeg, Canada.

出版信息

Transfusion. 1989 May;29(4):304-5. doi: 10.1046/j.1537-2995.1989.29489242794.x.

Abstract

Analysis of a family informative for chromosome 19 loci establishes that the Lutheran blood group locus (LU) lies between the third component of human complement (C3) and the secretor loci (SE). Previously published lod scores for C3:LU are increased from 2.94 to 3.80. The linkage relationships (zeta and theta) between C3, LU, and SE are examined, and the proposed order and approximate genetic distances are determined to be: pter--C3-10.6cM-cen-7.4cM-LU-9cM-SE--qter.

摘要

对一个19号染色体位点信息丰富的家族进行分析后确定,路德血型位点(LU)位于人类补体第三成分(C3)和分泌型位点(SE)之间。先前公布的C3:LU连锁值从2.94提高到了3.80。对C3、LU和SE之间的连锁关系(ζ和θ)进行了研究,确定其推测顺序和近似遗传距离为:短臂末端--C3-10.6厘摩-着丝粒-7.4厘摩-LU-9厘摩-SE--长臂末端。

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